Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502870 | 0.81 | KCNH2 (0.50) | — | |
| SCHEMBL7374792 | 0.79 | SIGMAR1 (0.49) | LTA4HTSHR | |
| SCHEMBL19322272 | 0.78 | FFAR1 (0.62) | FDFT1FFAR1LTA4HPLAAT3PLAAT5 | |
| SCHEMBL2201304 | 0.78 | FFAR1 (0.62) | FDFT1FFAR1LTA4HPLAAT3PLAAT5 | |
| SCHEMBL19322285 | 0.77 | FFAR1 (0.60) | FDFT1FFAR1LTA4HPLAAT3PLAAT5 | |
| SCHEMBL19322273 | 0.77 | FFAR1 (0.60) | FDFT1FFAR1LTA4HPLAAT3PLAAT5 | |
| SCHEMBL19322269 | 0.77 | FFAR1 (0.60) | FDFT1FFAR1LTA4HPLAAT3PLAAT5 | |
| SCHEMBL5534679 | 0.75 | FFAR1 (0.55) | FDFT1FFAR1LTA4HPLAAT3PLAAT5 | |
| SCHEMBL12040543 | 0.75 | FFAR1 (0.58) | FFAR1LTA4HPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11365631 | 0.74 | HDAC1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449539-B2 | Silsesquioxane derivative and production process for the same | CHISSO CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |