Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11908903 | 0.90 | CXCR4 (0.53) | CXCR4KMT2AMAN1B1KDM1AMAOB | |
| SCHEMBL13832686 | 0.90 | CXCR4 (0.53) | CXCR4KMT2AMAN1B1KDM1AMAOB | |
| SCHEMBL23023148 | 0.85 | SIGMAR1 (0.54) | KMT2ASIGMAR1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14740667 | 0.85 | KMT2A (0.49) | CXCR4KMT2ANPC1RAB9A | |
| SCHEMBL6450191 | 0.83 | MAN1B1 (0.57) | CXCR4KMT2AMAN1B1NPC1RAB9A | |
| SCHEMBL19314023 | 0.83 | EED (0.48) | CXCR4KMT2AEEDHTR6 | |
| Hydrochloric Acid SCHEMBL8503462 | 0.81 | SIGMAR1 (0.47) | KMT2ASIGMAR1HTR6 | |
| SCHEMBL10349210 | 0.81 | CXCR4 (0.65) | CXCR4KMT2AMAN1B1NPC1RAB9A | |
| SCHEMBL23023087 | 0.81 | CXCR4 (0.65) | CXCR4KMT2AMAN1B1NPC1RAB9A | |
| SCHEMBL22444295 | 0.81 | TSHR (0.50) | KMT2AEEDCHRNB2CHRNA4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027035-A1 | Dpp-Iv Inhibitors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2008-01-31 | — | — | US | disclosed |
| CN-1905868-A | DPP-IV inhibitors | GRAFFINITY PHARMACEUTICALS AG (CH) | 2007-01-31 | — | — | CN | disclosed |
| EP-1613304-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |
| EP-1541143-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2005-06-15 | — | — | EP | disclosed |
| EP-1209157-A1 | Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds | PFIZER INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1209157-A1 | Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds | PFIZER INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1209157-A1 | Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds | PFIZER INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| US-5703065-A | Heteroarylamino and heteroarylsulfonamido substituted 3-benyzlaminomethyl piperidines and related compounds | PFIZER INC. (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0719266-A1 | HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS | PFIZER INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0719266-A1 | HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS | PFIZER INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007908-A1 | HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS | PFIZER INC. (US) | 1995-03-23 | — | — | WO | disclosed |
| WO-1995007908-A1 | HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS | PFIZER INC. (US) | 1995-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027035-A1 | Dpp-Iv Inhibitors | DPP4, DPP7, DPP3 | CXCR4 448/4885KMT2A 2156/4885MAN1B1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.