Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003476 | 0.76 | CYP3A4 (0.50) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL29380985 | 0.73 | CYP3A4 (0.48) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL21280437 | 0.71 | SIRT1 (0.38) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL8724388 | 0.70 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL24632312 | 0.67 | CYP3A4 (0.37) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL5488537 | 0.67 | SIRT1 (0.38) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL10751824 | 0.67 | ALDH1A1 (0.38) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL1004841 | 0.66 | CYP3A4 (0.32) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL906696 | 0.66 | CYP3A4 (0.46) | SIRT1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL28841962 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449539-B2 | Silsesquioxane derivative and production process for the same | CHISSO CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |