Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954901 | 1.00 | KMT2A (0.44) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL4954897 | 1.00 | KMT2A (0.44) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL23057904 | 0.83 | KMT2A (0.43) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL9591757 | 0.74 | MAPT (0.77) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL9967743 | 0.74 | ALDH1A1 (0.55) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL10925626 | 0.70 | MAPT (0.44) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL21457142 | 0.69 | ALDH1A1 (0.60) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL21457141 | 0.69 | ALDH1A1 (0.60) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL13485338 | 0.69 | ESR1 (0.69) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL9610045 | 0.69 | ESR1 (0.69) | KMT2ALMNAMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026075-A2 | TREATMENT OF INTRACELLULAR BACTERIAL INFECTIONS WITH A PROTEIN KINASE INHIBITOR OR AN AS160 POLYPEPTIDE ACTIVATOR | VERENIGING HET NEDERLANDS KANKER INSTITUUT (NL) | 2008-03-06 | — | — | WO | disclosed |