Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924367 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL10925475 | 0.81 | AKR1C3 (0.46) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL10925092 | 0.81 | MCL1 (0.46) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL9591757 | 0.74 | MAPT (0.77) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL28449574 | 0.71 | MAPT (0.42) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL28449577 | 0.71 | MAPT (0.42) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL4954897 | 0.70 | KMT2A (0.44) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL4954892 | 0.70 | KMT2A (0.44) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL4954901 | 0.70 | KMT2A (0.44) | MAPTKMT2ALMNAKDM4EMEN1 | |
| SCHEMBL13485338 | 0.69 | ESR1 (0.69) | MAPTKMT2ALMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598083-A | INSECTICIDES, NEMATOCIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-01 | — | — | US | disclosed |