Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | MIF | P14174 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522068 | 0.87 | ESR1 (0.58) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL9522073 | 0.87 | ESR1 (0.58) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL11783121 | 0.86 | PTGS2 (0.46) | ESR1ESR2MIFKMT2APTGS2 | |
| Hydrochloric Acid SCHEMBL9522594 | 0.86 | ESR1 (0.56) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL11783130 | 0.86 | PTGS2 (0.46) | ESR1ESR2MIFKMT2APTGS2 | |
| Hydrochloric Acid SCHEMBL9522600 | 0.86 | ESR1 (0.56) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL23072695 | 0.85 | ESR1 (0.59) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL7273379 | 0.85 | ESR1 (0.59) | ESR1ESR2MIFKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL28049650 | 0.83 | ESR1 (0.56) | ESR1ESR2MIFKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL17360629 | 0.83 | ESR1 (0.56) | ESR1ESR2MIFKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318842-A1 | Cyclic Isodityrosine Derivatives | KEIO UNIVERSITY (JP) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318842-A1 | Cyclic Isodityrosine Derivatives | NR1H4, OAT, CYP3A5 | ESR1 2401/4885ESR2 2096/4885MIF 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.