Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANTXR2 | P58335 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060297 | 0.76 | KDM4E (0.53) | KDM4EGAAPKML3MBTL1ALDH1A1 | |
| SCHEMBL14243195 | 0.70 | KDM4E (0.59) | KDM4EGAAPKMALDH1A1HPGD | |
| SCHEMBL29386163 | 0.70 | ANTXR2 (0.50) | ANTXR2GAAALPLALPIL3MBTL1 | |
| SCHEMBL704787 | 0.70 | ANTXR2 (0.50) | ANTXR2GAAALPLALPIL3MBTL1 | |
| SCHEMBL2588111 | 0.68 | GAA (0.42) | ANTXR2KDM4EGAAALPLALPI | |
| SCHEMBL11976387 | 0.67 | KDM4E (0.53) | KDM4EGAAPKML3MBTL1ALDH1A1 | |
| SCHEMBL1520526 | 0.67 | ANTXR2 (1.00) | ANTXR2KDM4EGAAALPLALPI | |
| SCHEMBL31636206 | 0.67 | ANTXR2 (1.00) | ANTXR2KDM4EGAAALPLALPI | |
| SCHEMBL10181652 | 0.66 | MAOA (0.47) | KDM4EGAAPKMALPIL3MBTL1 | |
| SCHEMBL27157807 | 0.65 | KDM4E (0.37) | KDM4EGAAPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4030948-A | Polyimide containing silicones as protective coating on semiconductor device | MICROSI, INC. | 1977-06-21 | — | — | US | claimed |
| JP-2019365-A | — | — | None | — | — | JP | disclosed |
| JP-2019365-A | — | — | None | — | — | JP | disclosed |
| WO-2021079522-A1 | METHOD, KIT, AND PROGRAM FOR DETERMINING CHARACTERISTIC OF TUMOR CELL GROUP | 株式会社 東芝 | 2021-04-29 | — | — | WO | disclosed |
| US-7438950-B2 | Metallic pattern forming method and conductive pattern material | FUJIFILM CORPORATION (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20050266255-A1 | Conductive film forming method and conductive material | FUJI PHOTO FILM CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-20050266352-A1 | Forming a region in which a graft polymer, that directly bonds to a surface of a base material that includes a polyimide is generated in a pattern shape; imparting electroless plating catalyst or a precursor thereof and electroless plating so as to form a metallic film in the pattern shape | FUJI PHOTO FILM CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-6900239-B2 | Tumor chemopotentiation using isocoumarin derivatives | ILWZ ILEX PRODUCTS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040024015-A1 | Tumor radiosensitization and /or chemopotentiation using isocoumarin derivatives | GLBC LLC | 2004-02-05 | — | — | US | disclosed |
| EP-1363667-A1 | TUMOR RADIOSENSITIZATION AND/OR CHEMOPOTENTIATION USING ISOCOUMARIN DERIVATIVES | Ilex Oncology, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6589981-B2 | Combination treatment with ionizing radiation and/or chemotherapy | ILEX ONCOLOGY, INC. | 2003-07-08 | — | — | US | disclosed |
| US-20020165210-A1 | Tumor chemopotentiation using isocoumarin derivatives | GENZYME CORPORATION | 2002-11-07 | — | — | US | disclosed |
| WO-2002072143-A1 | TUMOR RADIOSENSITIZATION AND/OR CHEMOPOTENTIATION USING ISOCOUMARIN DERIVATIVES | ILEX ONCOLOGY, INC (US) | 2002-09-19 | — | — | WO | disclosed |
| US-20020019366-A1 | Tumor radiosensitization and/or chemopotentiation using isocoumarin derivatives | GLBC LLC | 2002-02-14 | — | — | US | disclosed |
| JP-H0219365-A | PRODUCTION OF INORGANIC ACID SALT OF DISULFIDE TYPE SIAMINE DERIVATIVE | TAKEDA CHEM IND LTD | 1990-01-23 | — | — | JP | disclosed |
| JP-H0219365-A | PRODUCTION OF INORGANIC ACID SALT OF DISULFIDE TYPE SIAMINE DERIVATIVE | TAKEDA CHEM IND LTD | 1990-01-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019366-A1 | Tumor radiosensitization and/or chemopotentiation using isocoumarin derivatives | HCCS, IDH2, IDH3A | ANTXR2 1599/4885KDM4E 3929/4885GAA 3618/4885 |
| US-20020165210-A1 | Tumor chemopotentiation using isocoumarin derivatives | MCL1, IDH2, MYADM | ANTXR2 805/4885KDM4E 3351/4885GAA 4136/4885 |
| US-20040024015-A1 | Tumor radiosensitization and /or chemopotentiation using isocoumarin derivatives | HCCS, IDH2, IDH3A | ANTXR2 1599/4885KDM4E 3929/4885GAA 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.