SCHEMBL704787

SCHEMBL704787

Oc1cc(O)c2c(O)cc(O)cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANTXR2 P58335 1/20 0.50
NQO2 P16083 1/20 0.46
BACE1 P56817 1/20 0.44
PTPN1 P18031 3/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NQO1 P15559 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 2/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
FASN P49327 2/20 0.36
CA9 Q16790 2/20 0.35
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386163 1.00 ANTXR2 (0.50) ANTXR2NQO2BACE1PTPN1MGAM
SCHEMBL29389056 0.79 ALDH1A1 (0.60) NQO2GAAL3MBTL1TDP1CYP3A4
SCHEMBL2023306 0.79 ALDH1A1 (0.60) NQO2GAAL3MBTL1TDP1CYP3A4
SCHEMBL20356048 0.73 MGAM (0.47) ANTXR2NQO2MGAMGAASI
SCHEMBL21582176 0.70 NQO2 (0.48) NQO2MGAMTDP1CYP3A4MEN1
SCHEMBL18940921 0.70 MGAM (0.44) ANTXR2NQO2MGAMGAASI
SCHEMBL16431563 0.70 NQO2 (0.48) ANTXR2NQO2PTPN1GAAALPL
SCHEMBL9551490 0.69 CYP3A4 (0.58) NQO2GAATDP1CYP3A4HPGD
SCHEMBL124871 0.69 CYP1A2 (0.48) NQO2BACE1TDP1CYP3A4HPGD
SCHEMBL23720784 0.69 NQO2 (0.54) ANTXR2NQO2BACE1NQO1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220211063-A1 FUNGAL STRAINS, PRODUCTION AND USES THEREOF UNIVERSITY OF NOTTINGHAM (GB) 2022-07-07 US claimed
EP-3956435-A1 FUNGAL STRAINS, PRODUCTION AND USES THEREOF University of Nottingham (GB) 2022-02-23 EP claimed
WO-2020212541-A1 FUNGAL STRAINS, PRODUCTION AND USES THEREOF UNIVERSITY OF NOTTINGHAM (GB) 2020-10-22 WO claimed
US-12540315-B2 Compositions and methods for using genetically modified enzymes RENEW BIOPHARMA, INC. (US) 2026-02-03 US disclosed
US-20250388854-A1 Compositions and methods for improved malonyl-CoA biosynthesis using 2-stage dynamic metabolic control UNIV DUKE (US) 2025-12-25 US disclosed
US-20250368695-A1 Atranorin biosynthesis gene derived from lichens and uses thereof INDUSTRY ACADEMIC COOPERATION FOUNDATION OF SUNCHON NATIONAL UNIV (KR) 2025-12-04 US disclosed
EP-4636004-A1 FLAME RETARDANT POLYURETHANE RESIN COMPOSITION AND SYNTHETIC ARTIFICIAL LEATHER USING SAME Seiren Co., Ltd. (JP) 2025-10-22 EP disclosed
US-20250277095-A1 CROSSLINKED POLYOLEFIN RESIN FOAM AND MULTILAYER BODY SEKISUI CHEMICAL CO., LTD. (JP) 2025-09-04 US disclosed
US-12385005-B2 Compositions and methods for improved malonyl-CoA biosynthesis using 2-stage dynamic metabolic control DUKE UNIVERSITY (US) 2025-08-12 US disclosed
US-12331177-B2 Crosslinked polyolefin resin foam and multilayer body SEKISUI CHEMICAL CO., LTD. (JP) 2025-06-17 US disclosed
WO-2025070304-A1 CURABLE RESIN COMPOSITION, RESIN MOLDED BODY, AND METHOD FOR PRODUCING RESIN MOLDED BODY 積水化学工業株式会社 2025-04-03 WO disclosed
US-20060183211-A1 Novel aromatic prenyltransferases, nucleic acids encoding same and uses therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. 2006-08-17 US disclosed
WO-2006081537-A2 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-08-03 WO disclosed
WO-2006081537-A2 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-08-03 WO disclosed
WO-2006046152-A2 METHODS FOR HETEROLOGOUS EXPRESSION OF SECONDARY METABOLITES GENE BRIDGES GMBH (DE) 2006-05-04 WO disclosed
EP-0635577-B1 Screen for inhibitors of melanin biosynthesis BASF AG (DE) 2003-08-27 EP disclosed
WO-2002069717-A1 UTILIZATION OF A CYCLOPROPANECARBOXYLIC ACID AMIDE DERIVATIVE AS MELANIN BIOSYNTHESIS INHIBITOR BAYER CROPSCIENCE AG (DE) 2002-09-12 WO disclosed
JP-2000342269-A MICROBIAL OR ENZYMATIC PRODUCTION OF 1,3,6,8- TETRAHYDROXYNAPHTHALENE MITSUBISHI RAYON CO LTD 2000-12-12 JP disclosed
JP-2000342269-A MICROBIAL OR ENZYMATIC PRODUCTION OF 1,3,6,8- TETRAHYDROXYNAPHTHALENE MITSUBISHI RAYON CO LTD 2000-12-12 JP disclosed
EP-0635577-A2 Screen for inhibitors of melanin biosynthesis AMERICAN CYANAMID COMPANY (US) 1995-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540315-B2 Compositions and methods for using genetically modified enzymes COASY, CYP4F3, CYP4F11 ANTXR2 4221/4885NQO2 322/4885BACE1 1544/4885
US-20250388854-A1 Compositions and methods for improved malonyl-CoA biosynthesis using 2-stage dynamic metabolic control MLYCD, COASY, PGD ANTXR2 3957/4885NQO2 387/4885BACE1 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.