Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.71 |
| ▸ | DPP4 | P27487 | 3/20 | 0.71 |
| ▸ | ACE | P12821 | 7/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040814 | 1.00 | DPP8 (0.71) | DPP8DPP4ACEDPP7ACE2 | |
| SCHEMBL9040522 | 0.97 | DPP4 (0.67) | DPP8DPP4ACEDPP7ACE2 | |
| SCHEMBL9040510 | 0.97 | DPP4 (0.67) | DPP8DPP4ACEDPP7ACE2 | |
| Methanesulfonamide SCHEMBL11099377 | 0.95 | DPP8 (0.65) | DPP8DPP4ACEDPP7ACE2 | |
| SCHEMBL7326774 | 0.93 | DPP8 (0.70) | DPP8DPP4ACEDPP7ACE2 | |
| Trifluoroacetic Acid SCHEMBL11102587 | 0.91 | DPP4 (0.60) | DPP8DPP4ACEDPP7ACE2 | |
| SCHEMBL7264291 | 0.90 | DPP8 (0.66) | DPP8DPP4ACEDPP7ACE2 | |
| Hydrochloric Acid SCHEMBL7264261 | 0.89 | DPP8 (0.65) | DPP8DPP4ACEDPP7ACE2 | |
| SCHEMBL9692365 | 0.89 | DPP8 (0.57) | DPP8DPP4ACEDPP7ACE2 | |
| SCHEMBL7322510 | 0.89 | ACE (0.75) | DPP8DPP4ACEDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249016-A1 | Use of GLP-2 in a combination treatment for bone-related disorders | SANOS BIOSCIENCE A/S | 2008-10-09 | — | — | US | disclosed |
| US-7371721-B2 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes | SANOS BIOSCIENCE A/S (DK) | 2008-05-13 | — | — | US | disclosed |
| US-20070135345-A1 | Use of GLP-2 for the treatment or prevention, of bone-related disorders | SANOS BIOSCIENCE A/S (DK) | 2007-06-14 | — | — | US | disclosed |
| US-7186683-B2 | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders | SANOS BIOSCIENCE A/S (DK) | 2007-03-06 | — | — | US | disclosed |
| US-20050282749-A1 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes | SANOS BIOSCIENCE A/S | 2005-12-22 | — | — | US | disclosed |
| US-6770620-B2 | ADMINISTERING POLYPEPTIDE; BONE DISORDERS | SANOS BIOSCIENCE A/S (DK) | 2004-08-03 | — | — | US | disclosed |
| EP-1414486-A2 | USE OF GLP-2 IN COMBINATION WITH ANOTHER THERAPEUTIC AGENT IN BONE-RELATED AND NUTRITION-RELATED DISORDERS | Osteometer Biotech AS (DK) | 2004-05-06 | — | — | EP | disclosed |
| US-20040052862-A1 | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders | SANOS BIOSCIENCE A/S (DE) | 2004-03-18 | — | — | US | disclosed |
| US-20020037836-A1 | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders | SANOS BIOSCIENCE A/S (DK) | 2002-03-28 | — | — | US | disclosed |
| WO-2002024214-A2 | USE OF GLP -2 IN COMBINATION WITH ANOTHER THERAPEUTIC AGENT IN BONE-RELATED AND NUTRITION-RELATED DISORDERS | OSTEOMETER BIOTECH A/S (DK) | 2002-03-28 | — | — | WO | disclosed |
| EP-0523449-B1 | Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative | DEGUSSA (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0279750-B1 | AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES | Asahi Breweries, Ltd. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0523449-A2 | Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative | DEGUSSA AG (DE) | 1993-01-20 | — | — | EP | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |
| EP-0132304-A2 | Hydroxy substituted peptide compounds | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |