Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.70 |
| ▸ | DPP4 | P27487 | 3/20 | 0.70 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.61 |
| ▸ | ACE | P12821 | 4/20 | 0.58 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264291 | 0.96 | DPP8 (0.66) | DPP8DPP4DPP7ACEPRSS8 | |
| Hydrochloric Acid SCHEMBL7264261 | 0.96 | DPP8 (0.65) | DPP8DPP4DPP7ACEPRSS8 | |
| SCHEMBL4955191 | 0.93 | DPP8 (0.71) | DPP8DPP4DPP7ACEPRSS8 | |
| SCHEMBL9040814 | 0.93 | DPP8 (0.71) | DPP8DPP4DPP7ACEPRSS8 | |
| SCHEMBL9040522 | 0.90 | DPP4 (0.67) | DPP8DPP4DPP7ACEACE2 | |
| SCHEMBL9040510 | 0.90 | DPP4 (0.67) | DPP8DPP4DPP7ACEACE2 | |
| SCHEMBL11200372 | 0.88 | DPP4 (0.60) | DPP8DPP4DPP7ACEPRSS8 | |
| Methanesulfonamide SCHEMBL11099377 | 0.88 | DPP8 (0.65) | DPP8DPP4DPP7ACEPRSS8 | |
| SCHEMBL6167239 | 0.85 | DPP4 (0.73) | DPP8DPP4DPP7ACEPRSS8 | |
| Trifluoroacetic Acid SCHEMBL11102587 | 0.85 | DPP4 (0.60) | DPP8DPP4DPP7ACEPRSS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279750-B1 | AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES | Asahi Breweries, Ltd. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |