Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.67 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.67 |
| ▸ | ACE | P12821 | 7/20 | 0.62 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040522 | 1.00 | DPP4 (0.67) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL4955191 | 0.97 | DPP8 (0.71) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL9040814 | 0.97 | DPP8 (0.71) | DPP4DPP8ACEDPP7ACE2 | |
| Methanesulfonamide SCHEMBL11099377 | 0.92 | DPP8 (0.65) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL11227109 | 0.91 | DPP4 (0.57) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL7326774 | 0.90 | DPP8 (0.70) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL11200372 | 0.88 | DPP4 (0.60) | DPP4DPP8ACEDPP7PREP | |
| Trifluoroacetic Acid SCHEMBL11102587 | 0.88 | DPP4 (0.60) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL7264291 | 0.87 | DPP8 (0.66) | DPP4DPP8ACEDPP7ACE2 | |
| SCHEMBL9574253 | 0.87 | ACE (0.76) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523449-B1 | Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative | DEGUSSA (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0523449-A2 | Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative | DEGUSSA AG (DE) | 1993-01-20 | — | — | EP | disclosed |