Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932564 | 0.85 | CSNK2A2 (0.48) | PTGS1PTGS2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL43717 | 0.85 | CSNK2A2 (0.48) | PTGS1PTGS2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL15318993 | 0.85 | CSNK2A2 (0.48) | PTGS1PTGS2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL15391718 | 0.83 | PTGS1 (0.51) | PTGS1PTGS2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL28981240 | 0.83 | CSNK2A2 (0.47) | PTGS1PTGS2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6047333 | 0.72 | KMT2A (0.42) | CSNK2A2CSNK2BCSNK2A1KMT2AMEN1 | |
| SCHEMBL27546535 | 0.72 | ALDH1A1 (0.41) | PTGS1PTGS2CYP1A2ALDH1A1HPGD | |
| Mercaptopropionic Acid SCHEMBL6324790 | 0.71 | ACE (0.48) | PTGS2CYP1A2FOLH1ACEALDH1A1 | |
| Mercaptopropionic Acid SCHEMBL7183577 | 0.71 | ACE (0.48) | PTGS2CYP1A2FOLH1ACEALDH1A1 | |
| SCHEMBL326701 | 0.70 | PTGS1 (0.47) | PTGS1PTGS2CYP1A2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399747-B1 | Peptides carrying substances across the blood brain barrier | SYNT:EM (FR) | 2008-07-15 | — | — | US | disclosed |
| EP-1135168-B1 | PEPTIDES CARRYING SUBSTANCES ACROSS THE BLOOD BRAIN BARRIER | SYNT EM SA (FR) | 2005-04-20 | — | — | EP | disclosed |