SCHEMBL43717

SCHEMBL43717

CC(C(=O)O)N1C(=O)C=CC1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
KDM4E B2RXH2 3/20 0.42
GAA P10253 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
LMNA P02545 2/20 0.40
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.38
DDAH1 O94760 1/20 0.38
NSD2 O96028 1/20 0.38
G6PD P11413 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15318993 1.00 CSNK2A2 (0.48) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL932564 1.00 CSNK2A2 (0.48) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL28981240 0.98 CSNK2A2 (0.47) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
Mercaptopropionic Acid SCHEMBL4955336 0.85 PTGS1 (0.39) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL6047333 0.85 KMT2A (0.42) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL15391718 0.82 PTGS1 (0.51) CSNK2A2CSNK2BCSNK2A1KDM4ELMNA
SCHEMBL22241544 0.81 LMNA (0.36) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL2611102 0.81 LMNA (0.36) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL28844372 0.80 TSHR (0.39) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1
SCHEMBL321357 0.79 LMNA (0.35) CSNK2A2CSNK2BCSNK2A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025243208-A2 PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF HOVIONE - FARMACIÊNCIA, SA (PT) 2025-11-27 WO claimed
CN-119823209-A Synthesis method of cyclic peptide containing maleimide acid 江苏金斯瑞生物科技有限公司 2025-04-15 CN claimed
CN-118290405-B Fluorescent probe for targeting SLC7A5 high-expression tumor and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2025-02-28 CN claimed
CN-118725337-A Hydroxyl-terminated hyperbranched polyester modified hindered phenol composite material and butyl rubber damping material prepared from same 艾华(浙江)新材料有限公司 2024-10-01 CN claimed
CN-118290405-A Fluorescent probe for targeting SLC7A5 high-expression tumor and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2024-07-05 CN claimed
CN-117838877-A Polypeptide P12-drug conjugate and application thereof in preparation of drugs for treating pancreatic cancer 中国医学科学院基础医学研究所 2024-04-09 CN claimed
US-11793886-B2 Hydrophilic linkers and conjugates thereof GLYKOS FINLAND OY (FI) 2023-10-24 US claimed
US-20230277612-A1 SAPONIN DERIVATIVES FOR USE IN MEDICINE SAPREME TECHNOLOGIES B.V. (NL) 2023-09-07 US claimed
US-20230272008-A1 NON-CLEAVABLE SUBSTANCE P CONJUGATES AND METHODS OF USE THEREOF VEIOVE ANIMAL HEALTH INC. 2023-08-31 US claimed
EP-4171642-A1 COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND AN ANTIBODY-SAPONIN CONJUGATE Sapreme Technologies B.V. (NL) 2023-05-03 EP claimed
US-20030170250-A1 Local delivery of long lasting therapeutic agents EZRIN ALAN M (US) 2003-09-11 US claimed
US-20020039999-A1 Antinociceptive agent derivative CONJUCHEM, LLC 2002-04-04 US claimed
US-20020018751-A1 CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING CONJUCHEM, INC. (CA) 2002-02-14 US claimed
US-20010018420-A1 Method for alleviating pain or providing an analgesic effect in a patient CONJUCHEM, LLC 2001-08-30 US claimed
US-20010018421-A1 Conjugate comprising an antinociceptive agent covalently bonded to a blood component CONJUCHEM, LLC 2001-08-30 US claimed
EP-1042003-A1 DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO Conjuchem, Inc. (CA) 2000-10-11 EP claimed
US-6107489-A CHEMICALLY REACTIVE TRIPEPTIDE INTERMEDIATES WHICH CAN REACT WITH AVAILABLE REACTIVE FUNCTIONALITIES ON BLOOD COMPONENTS TO FORM COVALENT LINKAGES, THE RESULTING CONJUGATES HAVE RENIN INHIBITION ACTIVITY FOR EXTENDED PERIODS OF TIME CONJUCHEM, INC. (CA) 2000-08-22 US claimed
EP-1007561-A2 NOVEL CONJUGATES OF OPIOIDS AND ENDOGENOUS CARRIERS Conjuchem, Inc. (CA) 2000-06-14 EP claimed
WO-1999048536-A2 DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO CONJUCHEM, INC. (CA) 1999-09-30 WO claimed
WO-1999024074-A2 NOVEL CONJUGATES OF OPIOIDS AND ENDOGENOUS CARRIERS CONJUCHEM, INC. (CA) 1999-05-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010018420-A1 Method for alleviating pain or providing an analgesic effect in a patient OPRK1, OPRL1, OGFR CSNK2A2 2981/4885CSNK2B 3206/4885CSNK2A1 3129/4885
US-20230277612-A1 SAPONIN DERIVATIVES FOR USE IN MEDICINE HAVCR2, HCCS, PYGL CSNK2A2 2386/4885CSNK2B 2243/4885CSNK2A1 2316/4885
US-11793886-B2 Hydrophilic linkers and conjugates thereof CD44, FOLR2, SLCO2B1 CSNK2A2 3356/4885CSNK2B 3050/4885CSNK2A1 3737/4885
US-20020018751-A1 CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING FABP3, VCAM1, TAGLN2 CSNK2A2 3515/4885CSNK2B 3521/4885CSNK2A1 3759/4885
US-20020039999-A1 Antinociceptive agent derivative OPRK1, OPRL1, OGFR CSNK2A2 3031/4885CSNK2B 3341/4885CSNK2A1 3035/4885
US-20010018421-A1 Conjugate comprising an antinociceptive agent covalently bonded to a blood component OPRK1, OPRL1, OGFR CSNK2A2 2436/4885CSNK2B 2654/4885CSNK2A1 2476/4885
US-20030170250-A1 Local delivery of long lasting therapeutic agents VEGFA, MMP8, MMP1 CSNK2A2 3130/4885CSNK2B 3404/4885CSNK2A1 2962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.