Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063381 | 0.81 | NSD2 (0.49) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL728509 | 0.80 | KMT2A (0.47) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL4953462 | 0.80 | MEN1 (0.55) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL4955038 | 0.80 | EGFR (0.32) | L3MBTL1RAB9ATDP1SMN1; SMN2MAPT | |
| SCHEMBL4954956 | 0.80 | NSD2 (0.41) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL1906212 | 0.77 | MAPT (0.56) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL4955660 | 0.77 | MEN1 (0.42) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL11408020 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AHTTNSD2LMNA | |
| SCHEMBL4958638 | 0.75 | PABPC1 (0.41) | ALDH1A1KMT2ALMNAL3MBTL1RAB9A | |
| SCHEMBL5420918 | 0.75 | KMT2A (0.57) | ALDH1A1KMT2AHTTNSD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968602-B2 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2018-05-15 | — | — | US | claimed |
| US-20140030317-A1 | MODULATION OF CELL FATES AND ACTIVITIES BY PHTHALAZINEDIONES | Occhiuti & Rohlicek LLP | 2014-01-30 | — | — | US | claimed |
| US-7326690-B2 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2008-02-05 | — | — | US | claimed |
| US-20070142303-A1 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2007-06-21 | — | — | US | claimed |