Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940203 | 1.00 | CYP2C19 (0.55) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11762901 | 0.85 | CYP2C19 (0.54) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23638096 | 0.84 | AKR1C3 (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14269527 | 0.84 | CYP2C19 (0.57) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31666241 | 0.81 | AKR1C3 (0.68) | CYP2C9AKR1C3HTTKDM4E | |
| SCHEMBL8746671 | 0.81 | AKR1C3 (0.68) | CYP2C9AKR1C3HTTKDM4E | |
| SCHEMBL3893886 | 0.81 | AKR1C3 (0.68) | CYP2C9AKR1C3HTTKDM4E | |
| SCHEMBL439384 | 0.80 | AKR1C3 (0.49) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2046747 | 0.80 | AKR1C3 (0.49) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL398055 | 0.79 | KMT2A (0.49) | AKR1C3ALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207942-A1 | USING IN COORDINATION CATALYST CONTAINING TRANSITION METAL FOR HYDROGENATION, PHASE TRANSFER, CYANATION,BORATING, HYDROSILYLATION | KAISER-WILHELM-PLATZ 1 (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-0612758-B1 | Ferrocenyl diphosphines as ligands for homogeneous catalysts | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-09 | — | — | EP | disclosed |
| US-RE37344-E1 | FOR FORMING COMPLEXES WITH IRIDIUM OR RHODIUM WHICH ARE USED FOR ENANTIOSELECTIVE HYDROGENATION CATALYSTS FOR HOMOGENEOUS HYDROGENATION OF PROCHIRAL UNSATURATED COMPOUNDS | NOVARTIS CORPORATION | 2001-08-28 | — | — | US | disclosed |
| EP-0646590-B1 | Ferrocenyldiphosphines substituted with fluoroalkyl groups as ligands for homogeneous catalysts | NOVARTIS AG (CH) | 1999-08-25 | — | — | EP | disclosed |
| EP-0564406-B1 | Ferrocenyldiphosphine as ligands for homogeneous catalysts | NOVARTIS AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| US-5583241-A | FORM COMPLEXES WITH RHODIUM OR IRIDIUM USED FOR HYDROGENATION CATALYSTS | CIBA-GEIGY CORPORATION (US) | 1996-12-10 | — | — | US | disclosed |
| US-5565594-A | Ferrocene diphosphines as ligands for homogeneous catalysts | CIBA-GEIGY CORPORATION (US) | 1996-10-15 | — | — | US | disclosed |
| US-5563308-A | Ferrocene diphosphines as ligands for homogeneous catalysts | CIBA-GEIGY CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5563309-A | Ferrocenyl diphosphines as ligands for homogeneous catalysts | CIBA-GEIGY CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5466844-A | Ferrocene diphosphines as ligands for homogeneous catalysts | CIBA-GEIGY CORPORATION (US) | 1995-11-14 | — | — | US | disclosed |
| US-5463097-A | Ferrocenyl diphosphines as ligands for homogeneous catalysts | CIBA-GEIGY CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0646590-A1 | Ferrocenyldiphosphines substituted with fluoroalkyl groups as ligands for homogeneous catalysis | CIBA-GEIGY AG (CH) | 1995-04-05 | — | — | EP | disclosed |
| US-5371256-A | With rhodium and iridium | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0612758-A1 | Ferrocenyl/diphosphines as ligands for homogeneous catalysts | CIBA-GEIGY AG (CH) | 1994-08-31 | — | — | EP | disclosed |
| EP-0564406-A1 | Ferrocenyldiphosphine as ligands for homogeneous catalysts | CIBA-GEIGY AG (CH) | 1993-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207942-A1 | USING IN COORDINATION CATALYST CONTAINING TRANSITION METAL FOR HYDROGENATION, PHASE TRANSFER, CYANATION,BORATING, HYDROSILYLATION | HK1, GCK, HIRA | CYP2C19 2573/4885CYP1A2 2888/4885CYP3A4 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.