Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 8/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2046747 | 1.00 | AKR1C3 (0.49) | AKR1C3CYP2C9APEX1FABP4ESR1 | |
| SCHEMBL23638096 | 0.81 | AKR1C3 (0.53) | AKR1C3CYP2C9APEX1DHODHTRPM8 | |
| SCHEMBL396115 | 0.80 | PSIP1 (0.47) | AKR1C3CYP2C9APEX1KDM4EALDH1A1 | |
| SCHEMBL396113 | 0.80 | PSIP1 (0.47) | AKR1C3CYP2C9APEX1KDM4EALDH1A1 | |
| SCHEMBL6940203 | 0.80 | CYP2C19 (0.55) | AKR1C3CYP2C9DHODHTRPM8KDM4E | |
| SCHEMBL4956211 | 0.80 | CYP2C19 (0.55) | AKR1C3CYP2C9DHODHTRPM8KDM4E | |
| SCHEMBL8746671 | 0.78 | AKR1C3 (0.68) | AKR1C3CYP2C9APEX1KDM4EMAPT | |
| SCHEMBL31666241 | 0.78 | AKR1C3 (0.68) | AKR1C3CYP2C9APEX1KDM4EMAPT | |
| SCHEMBL3893886 | 0.78 | AKR1C3 (0.68) | AKR1C3CYP2C9APEX1KDM4EMAPT | |
| SCHEMBL398055 | 0.76 | KMT2A (0.49) | AKR1C3APEX1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303331-B1 | OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME | ALCON INC (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-2292672-B1 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | CIS PHARMA AG (CH) | 2018-05-09 | — | — | EP | claimed |
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | claimed |
| EP-2341102-B1 | Thermoplastic resin composition revealing improved impact strength and melt flow property | CHEIL IND INC (KR) | 2015-12-02 | — | — | EP | claimed |
| US-8907013-B2 | Polycarbonate resin composition and molded product using the same | CHEIL INDUSTRIES INC. (KR) | 2014-12-09 | — | — | US | claimed |
| EP-2341104-B1 | Polycarbonate resin composition with excellent scratch resistance and impact strength | CHEIL IND INC (KR) | 2014-11-12 | — | — | EP | claimed |
| US-8835558-B2 | Polylactic acid/polycarbonate resin composition and molded product made using the same | CHEIL INDUSTRIES INC. (KR) | 2014-09-16 | — | — | US | claimed |
| EP-2199342-B1 | Polylactic acid/polycarbonate resin composition and molded product made using the same | CHEIL IND INC (KR) | 2014-07-30 | — | — | EP | claimed |
| US-8735490-B2 | Thermoplastic resin composition having improved impact strength and melt flow properties | CHEIL INDUSTRIES INC. (KR) | 2014-05-27 | — | — | US | claimed |
| EP-2204412-B1 | Polycarbonate resin composition with improved scratch resistance and melt flow index | CHEIL IND INC (KR) | 2012-08-29 | — | — | EP | claimed |
| US-20110281995-A1 | Polycarbonate Resin Composition and Molded Product Using the Same | CHEIL INDUSTRIES INC. (KR) | 2011-11-17 | — | — | US | claimed |
| EP-2341102-A1 | Thermoplastic resin composition revealing improved impact strength and melt flow property | Cheil Industries Inc. (KR) | 2011-07-06 | — | — | EP | claimed |
| US-20110160377-A1 | Thermoplastic Resin Composition Having Improved Impact Strength and Melt Flow Properties | CHEIL INDUSTRIES INC. (KR) | 2011-06-30 | — | — | US | claimed |
| US-20100160559-A1 | Polylactic Acid/Polycarbonate Resin Composition and Molded Product Made Using the Same | CHEIL INDUSTRIES INC. (KR) | 2010-06-24 | — | — | US | claimed |
| EP-2199342-A2 | Polylactic acid/polycarbonate resin composition and molded product made using the same | Cheil Industries Inc. (KR) | 2010-06-23 | — | — | EP | claimed |
| EP-1080382-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2009-07-08 | — | — | EP | claimed |
| EP-1664855-B1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | claimed |
| EP-0914169-B1 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LAB INC (US) | 2003-07-30 | — | — | EP | claimed |
| EP-2455426-B1 | POLYCARBONATE RESIN COMPOSITION HAVING HIGH GLOSS AND IMPACT RESISTANCE AND GOOD SURFACE PROPERTIES, AND MOLDED ARTICLE USING THE SAME | LOTTE ADVANCED MAT CO LTD (KR) | 2021-01-06 | — | — | EP | disclosed |
| US-20090287306-A1 | Optical hydrogel material with photosensitizer and method for modifying the refractive index | MEDICIS PHARMACEUTICAL CORPORATION | 2009-11-19 | — | — | US | disclosed |