Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | PRKACA | P17612 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147408 | 1.00 | HIF1A (0.72) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL5148577 | 1.00 | HIF1A (0.72) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL16387681 | 0.93 | HIF1A (0.66) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL13659971 | 0.92 | HIF1A (0.69) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL12087287 | 0.91 | HIF1A (0.70) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL1535419 | 0.91 | HIF1A (0.75) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL21790141 | 0.91 | HIF1A (0.75) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL13659919 | 0.90 | HIF1A (0.70) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL13656023 | 0.90 | LMNA (0.66) | HIF1ANR3C1PGRLMNACYP3A4 | |
| SCHEMBL12087295 | 0.90 | HIF1A (0.84) | HIF1ANR3C1PGRLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116077669-A | Glucocorticoid nano-lipid carrier for treating arthralgia, preparation method and application thereof | 中南大学湘雅医院 | 2023-05-09 | — | — | CN | claimed |
| CN-116077669-A | Glucocorticoid nano-lipid carrier for treating arthralgia, preparation method and application thereof | 中南大学湘雅医院 | 2023-05-09 | — | — | CN | disclosed |
| US-8227452-B2 | Use of a steroid prodrug for the treatment of disease of the posterior segment of the eye | NOVAGALI PHARMA SA (FR) | 2012-07-24 | — | — | US | disclosed |
| CN-101332186-A | Medicine composition for injecting triamcinolone acetonide palmitate lipid microsphere and preparation method thereof | GUANGZHOU BEI S MEDICINE CO LT (CN) | 2008-12-31 | — | — | CN | disclosed |
| WO-2008035246-A2 | COMPOSITIONS CONTAINING QUATERNARY AMMONIUM COMPOUNDS | NOVAGALI PHARMA SA (FR) | 2008-03-27 | — | — | WO | disclosed |
| US-20080025941-A1 | Compositions containing quaternary ammonium compounds | NOVAGALI PHARMA SA (FR) | 2008-01-31 | — | — | US | disclosed |
| WO-2007138113-A1 | USE OF A STEROID PRODRUG FOR THE TREATMENT OF DISEASE OF THE POSTERIOR SEGMENT OF THE EYE | NOVAGALI PHARMA SA (FR) | 2007-12-06 | — | — | WO | disclosed |
| US-20070280995-A1 | Use of a steroid prodrug for the treatment of disease of the posterior segment of the eye | NOVAGALI PHARMA SA (FR) | 2007-12-06 | — | — | US | disclosed |