Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.59 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.56 |
| ▸ | FPR3 | P25089 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223216 | 0.97 | HCRTR1 (0.60) | OPRD1HCRTR1HCRTR2FPR3FPR2 | |
| SCHEMBL6223213 | 0.97 | HCRTR1 (0.60) | OPRD1HCRTR1HCRTR2FPR3FPR2 | |
| SCHEMBL12311356 | 0.86 | OPRD1 (0.53) | OPRD1HCRTR2FPR3FPR2NPC1 | |
| SCHEMBL6222525 | 0.86 | ALDH1A1 (0.54) | OPRD1HCRTR1HCRTR2FPR3FPR2 | |
| SCHEMBL4664834 | 0.84 | KDM4E (0.65) | OPRD1HCRTR1HCRTR2FPR3FPR2 | |
| SCHEMBL6223221 | 0.81 | KDM4E (0.64) | OPRD1HCRTR1HCRTR2FPR3FPR2 | |
| SCHEMBL6223223 | 0.81 | KDM4E (0.64) | OPRD1HCRTR1HCRTR2FPR3FPR2 | |
| SCHEMBL14365902 | 0.81 | OPRD1 (0.54) | OPRD1FPR3FPR2NPC1SMN1; SMN2 | |
| SCHEMBL13853607 | 0.81 | OPRD1 (0.54) | OPRD1FPR3FPR2NPC1SMN1; SMN2 | |
| SCHEMBL13853613 | 0.81 | OPRD1 (0.54) | OPRD1FPR3FPR2NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027035-A1 | Dpp-Iv Inhibitors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20080027035-A1 | Dpp-Iv Inhibitors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20080027035-A1 | Dpp-Iv Inhibitors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1613304-B1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS CH (CH) | 2007-09-12 | — | — | EP | disclosed |
| EP-1613304-B1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS CH (CH) | 2007-09-12 | — | — | EP | disclosed |
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |
| EP-1541143-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027035-A1 | Dpp-Iv Inhibitors | DPP4, DPP7, DPP3 | OPRD1 1248/4885HCRTR1 2683/4885HCRTR2 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.