Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522078 | 0.95 | OPRM1 (0.47) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL6229229 | 0.93 | OPRM1 (0.46) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL483007 | 0.93 | OPRM1 (0.46) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL4339042 | 0.91 | OPRM1 (0.45) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL17925986 | 0.91 | — | — | |
| SCHEMBL16190003 | 0.91 | — | — | |
| SCHEMBL4289914 | 0.80 | SMN1; SMN2 (0.50) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL20941858 | 0.79 | OPRM1 (0.41) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9986841 | 0.78 | OR51E2 (0.34) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL17101303 | 0.78 | OPRM1 (0.40) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879879-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | Virochem Pharma Inc. (CA) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119646-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC. (CA) | 2006-11-16 | — | — | WO | disclosed |