Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL495715 | 1.00 | SCN9A (0.49) | SCN9APRMT5WDR77DRD2KDM4E | |
| SCHEMBL496319 | 0.84 | KLK5 (0.54) | PRMT5WDR77DRD2 | |
| SCHEMBL496318 | 0.84 | KLK5 (0.54) | PRMT5WDR77DRD2 | |
| SCHEMBL12635649 | 0.78 | KLK5 (0.55) | PRMT5WDR77DRD2 | |
| SCHEMBL496566 | 0.78 | PRMT5 (0.51) | PRMT5WDR77DRD2KDM4EMAPK1 | |
| SCHEMBL496038 | 0.78 | SCN9A (0.40) | SCN9AKDM4E | |
| SCHEMBL496036 | 0.78 | SCN9A (0.40) | SCN9AKDM4E | |
| Hydrochloric Acid SCHEMBL496305 | 0.77 | PRMT5 (0.50) | PRMT5WDR77DRD2KDM4EMAPK1 | |
| SCHEMBL495865 | 0.77 | KLK5 (0.43) | SCN9A | |
| SCHEMBL495863 | 0.77 | KLK5 (0.43) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910317-B1 | 1-AMINO LINKED COMPOUNDS | LILLY CO ELI (US) | 2013-07-03 | — | — | EP | disclosed |
| US-8106090-B2 | Antidiabetic agents; prevent of non-insulin dependent diabetes | ELI LILLY AND COMPANY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20080207735-A1 | 1-Amino Linked Compounds | ELI LILLY AND COMPANY | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207735-A1 | 1-Amino Linked Compounds | DPP4, DPP3, DPP9 | SCN9A 467/4885PRMT5 1142/4885WDR77 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.