Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HK2 | P52789 | 5/20 | 0.44 |
| ▸ | HK1 | P19367 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PYGB | P11216 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954637 | 1.00 | LMNA (0.47) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| N-Acetylglucosamine SCHEMBL29263425 | 0.85 | MAPK1 (0.56) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| N-Acetylglucosamine SCHEMBL7745223 | 0.82 | MAPK1 (0.56) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL8770830 | 0.82 | PYGB (0.51) | CA12CA1CA2CA9PYGB | |
| N-Acetylglucosamine SCHEMBL29144670 | 0.80 | MAPK1 (0.47) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| N-Acetylglucosamine SCHEMBL27711409 | 0.79 | MAPK1 (0.50) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL29852070 | 0.79 | LMNA (0.56) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL4955152 | 0.79 | LMNA (0.56) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL4955133 | 0.79 | LMNA (0.56) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| N-Acetylglucosamine SCHEMBL27889883 | 0.78 | MAPK1 (0.52) | LMNAKDM4ECYP2D6CYP2C19HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054528-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |