Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959938 | 0.89 | CCR3 (0.42) | PRMT5WDR77GRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4957412 | 0.88 | FAAH (0.47) | PRMT5WDR77GRIN2BL3MBTL1RAB9A | |
| SCHEMBL4958259 | 0.82 | FAAH (0.41) | PRMT5WDR77GRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4958536 | 0.82 | FAAH (0.41) | PRMT5WDR77GRIN2BL3MBTL1RAB9A | |
| SCHEMBL4959447 | 0.81 | SLC6A2 (0.46) | PRMT5WDR77GRIN2B | |
| SCHEMBL4959460 | 0.81 | MEN1 (0.41) | PRMT5WDR77GRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4958808 | 0.80 | SMN1; SMN2 (0.43) | PRMT5WDR77GRIN2BRAB9ACYP2C9 | |
| SCHEMBL4958347 | 0.79 | CCR3 (0.42) | PRMT5WDR77GRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4959675 | 0.77 | FAAH (0.39) | PRMT5WDR77RAB9ACYP2C9CYP2C19 | |
| SCHEMBL4961290 | 0.77 | SLC6A2 (0.44) | GRIN2BFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |