Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958259 | 0.92 | FAAH (0.41) | MEN1KMT2AGRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4957412 | 0.92 | FAAH (0.47) | SMN1; SMN2MEN1KMT2AGRIN2BCYP2C9 | |
| SCHEMBL4959460 | 0.90 | MEN1 (0.41) | MEN1KMT2AGRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4958536 | 0.89 | FAAH (0.41) | MEN1KMT2AGRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4958347 | 0.88 | CCR3 (0.42) | MEN1KMT2AGRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4959344 | 0.88 | MGLL (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL4959675 | 0.87 | FAAH (0.39) | MEN1KMT2ACYP2C9CYP2C19CCR3 | |
| SCHEMBL4963114 | 0.84 | TACR1 (0.41) | MEN1KMT2AGRIN2BCYP2C9CYP2C19 | |
| SCHEMBL4958443 | 0.83 | POLB (0.39) | SMN1; SMN2GRIN2BCYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4959588 | 0.81 | PSEN1 (0.38) | CCR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |