Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620749 | 0.69 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL1966927 | 0.69 | CHRNB2 (0.41) | CHRNB2CHRNA4KDM4AKDM4BKDM5C | |
| SCHEMBL25434056 | 0.66 | CHRNB2 (0.39) | CHRNB2CHRNA4KDM4AKDM4BKDM5C | |
| SCHEMBL26620761 | 0.65 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL1088152 | 0.64 | SIGMAR1 (0.52) | CHRNB2CHRNA4 | |
| SCHEMBL2432002 | 0.64 | — | — | |
| SCHEMBL17922174 | 0.63 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL16600475 | 0.63 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNA7 | |
| Bromide SCHEMBL8691876 | 0.63 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNA7 | |
| Bromide SCHEMBL8686784 | 0.63 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039882-A1 | A COMBINATION OF NIACIN AND A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST | SANOFI-AVENTIS U.S. LLC (US) | 2008-04-03 | — | — | WO | disclosed |