⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862134 | 0.91 | — | — | |
| SCHEMBL1509652 | 0.80 | — | — | |
| SCHEMBL1131574 | 0.73 | ENPEP (0.36) | — | |
| SCHEMBL484146 | 0.73 | — | — | |
| SCHEMBL23467011 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL5400057 | 0.71 | — | — | |
| SCHEMBL471954 | 0.71 | — | — | |
| SCHEMBL17993940 | 0.71 | — | — | |
| SCHEMBL284090 | 0.71 | — | — | |
| SCHEMBL726672 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228629-A | Substituted cyclopentyl -azines as CaSR- active compounds | LEO PHARMA AS | 2013-07-31 | — | — | CN | claimed |
| US-20160374945-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS | BEND RESEARCH, INC. (US) | 2016-12-29 | — | — | US | disclosed |
| US-9468604-B2 | Pharmaceutical compositions of dispersions of drug and neutral polymers | BEND RESEARCH, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20140210117-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUG AND NEUTRAL POLYMERS | BEND RESEARCH, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-20130267516-A1 | SUBSTITUTED CYCLOPENTYL-AZINES AS CASR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2013-10-10 | — | — | US | disclosed |
| EP-2643298-A1 | SUBSTITUTED CYCLOPENTYL - AZINES AS CASR- ACTIVE COMPOUNDS | Leo Pharma A/S (DK) | 2013-10-02 | — | — | EP | disclosed |
| CN-103228629-A | Substituted cyclopentyl -azines as CaSR- active compounds | LEO PHARMA AS | 2013-07-31 | — | — | CN | disclosed |
| WO-2012069402-A1 | SUBSTITUTED CYCLOPENTYL - AZINES AS CASR- ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2012-05-31 | — | — | WO | disclosed |
| CN-101501092-B | Catalyst composition for polyurethane resin production and method for producing polyurethane resin | TOSOH CORP | 2011-09-28 | — | — | CN | disclosed |
| CN-101501092-A | Catalyst composition for polyurethane resin production and method for producing polyurethane resin | TOSOH CORP (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-1131216-C | Condensed 1, 2-indanes and their pharmaceutically acceptable salts, process for their preparation and their use | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| EP-1358181-A1 | SUBSTITUTED PYRROLIDINES AS CCR-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| US-20030199532-A1 | 2,4-substituted pyrrolidine derivatives-CCR-3 receptor antagonists | KERTESZ DENIS JOHN (US) | 2003-10-23 | — | — | US | disclosed |
| US-20030091643-A1 | Amorphous mixture of acid sensitive drug and addition polymer; chemical resistance, stability | BEND RESEARCH, INC. | 2003-05-15 | — | — | US | disclosed |
| US-6552028-B2 | Inhibiting the binding of eotaxin to chemokine-3 (ccr-3) receptor; antiasthmatics | SYNTEX (U.S.A.) LLC | 2003-04-22 | — | — | US | disclosed |
| WO-2003000235-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| US-20020198255-A1 | 2,4-substituted pyrrolidine derivatives-CCR-3 receptor antagonists | SYNTEX (U.S.A.) LLC | 2002-12-26 | — | — | US | disclosed |
| WO-2002050064-A1 | SUBSTITUTED PYRROLIDINES AS CCR-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-27 | — | — | WO | disclosed |
| CN-1272873-A | Laundry detergent compositions with amino acid based polymers to provide appearance and integrity benefits to fabrics laundered therewith | PROCTER & GAMBLE (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1130903-A | Condensed 1,2-indene dihydride and its salt for medicine | TAIHO PHARMACEUTICAL CO LTD (JP) | 1996-09-11 | — | — | CN | disclosed |