Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3487695 | 0.98 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL45077 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29452929 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL14207708 | 0.84 | KMT2A (0.69) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL1686048 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL4055817 | 0.82 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL30602595 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL433102 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL31005453 | 0.80 | KMT2A (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL4737383 | 0.76 | NPC1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6027874-A | IMMUNOASSAY BY CONTACTING SAMPLE WITH CONJUGATE OF GLYCOSYLATED LABELING ENZYMES AND IMMUNOLOGICAL SUBSTANCE, AND DETECTING COMPLEX FORMED; FOR INCREASED SENSITIVITY OF VIRAL INFECTIONS | PASTEUR SANOFI DIAGNOSTICS (FR) | 2000-02-22 | — | — | US | claimed |
| EP-0398305-B1 | Anthracycline conjugates having a novel linker and methods for their production | BRISTOL MYERS SQUIBB CO (US) | 1997-03-19 | — | — | EP | claimed |
| EP-0328147-B1 | Anthracycline immunoconjugates having a novel linker and methods for their production | BRISTOL MYERS SQUIBB CO (US) | 1994-05-11 | — | — | EP | claimed |
| CN-119923278-A | Dendrimer compositions for targeted delivery of fantasy therapeutic agents | 约翰霍普金斯大学 | 2025-05-02 | — | — | CN | disclosed |
| CN-119789874-A | Cannabis for targeted delivery vegetable dendrimer composition | 约翰霍普金斯大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119053344-A | Dendrimer compositions for targeted delivery of therapeutic agents to neurons | 约翰霍普金斯大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-111867633-B | Covalent anesthetic-polymer conjugates for achieving prolonged local anesthesia | 儿童医学中心公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-115103689-A | Dendrimer compositions and methods for drug delivery | 阿什瓦塔治疗股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| US-20220160874-A1 | NEUROTROPHIC FACTOR PROTEIN CONJUGATES AND RELATED EMBODIMENTS | TECHNICAL UNIVERSITY OF DENMARK (DE) | 2022-05-26 | — | — | US | disclosed |
| EP-3946413-A1 | NEUROTROPHIC FACTOR PROTEIN CONJUGATES AND RELATED EMBODIMENTS | Technical University of Denmark (DK) | 2022-02-09 | — | — | EP | disclosed |
| CN-111867633-A | Covalent narcotic-polymer conjugates for achieving prolonged local anesthesia | 儿童医学中心公司 | 2020-10-30 | — | — | CN | disclosed |
| US-5955605-A | DIAGNOSIS AND TREATMENT OF CANCER WITH CONJUGATES | NEORX CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0695189-B1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE WITH IFN-GAMMA INHIBITORS | GENENTECH INC (US) | 1998-11-25 | — | — | EP | disclosed |
| US-5630996-A | Two-step pretargeting methods using improved biotin-active agent conjugates | NEORX CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0398305-B1 | Anthracycline conjugates having a novel linker and methods for their production | BRISTOL MYERS SQUIBB CO (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5608060-A | DIAGNOSIS AND TREATMENT OF CANCER; DRUG DELIVERY TO TARGET CELLS | NEORX CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0695189-A1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE WITH IFN-GAMMA INHIBITORS | GENENTECH, INC. (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0646019-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-04-05 | — | — | EP | disclosed |
| WO-1994014467-A1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE WITH IFN-GAMMA INHIBITORS | GENENTECH, INC. (US) | 1994-07-07 | — | — | WO | disclosed |
| WO-1993025240-A2 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1993-12-23 | — | — | WO | disclosed |