Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | PRNP | P04156 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602595 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL16564081 | 0.90 | ALDH1A1 (0.81) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL2678377 | 0.88 | ALDH1A1 (0.79) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL8916154 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL21768397 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL20202251 | 0.84 | ALDH1A1 (0.72) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL98030 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL4055817 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL29811281 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| Succinic Acid SCHEMBL28529727 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2AMAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003701-A1 | COVALENT MODIFICATION AND CONJUGATION OF LUCIFERASE | CARDIOGENICS INC. (CA) | 2010-01-07 | — | — | US | claimed |
| US-20070254311-A1 | Covalent modification and conjugation of luciferase | CARDIOGENICS INC. (CA) | 2007-11-01 | — | — | US | claimed |
| EP-0184701-B1 | A method for determining a ligand | HOECHST CELANESE CORP (US) | 1994-06-08 | — | — | EP | claimed |
| EP-0440647-A1 | LABELED NUCLEIC ACID PROBE | BIOGEN, INC. (US) | 1991-08-14 | — | — | EP | claimed |
| WO-1990007924-A1 | PROTEIN COUPLING TO LIPID VESICLES | MICRO VESICULAR SYSTEMS, INC. (US) | 1990-07-26 | — | — | WO | claimed |
| WO-1989012110-A1 | LABELED NUCLEIC ACID PROBE | BIOGEN, INC. (US) | 1989-12-14 | — | — | WO | claimed |
| EP-3473249-A1 | CROSSLINKABLE DENDRIMERS | Wayne State University (US) | 2019-04-24 | — | — | EP | disclosed |
| US-20170028075-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | Ashvattha Therapeutics, Inc. | 2017-02-02 | — | — | US | disclosed |
| US-9526794-B2 | Injectable dendrimer hydrogel nanoparticles | WAYNE STATE UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| CN-106103731-A | Compositions and methods for providing active telomerase to cells in vivo | 特洛雷根公司 | 2016-11-09 | — | — | CN | disclosed |
| US-20130136697-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | NATIONAL INSTITUTES OF HEALTH (US) | 2013-05-30 | — | — | US | disclosed |
| EP-2595957-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-05-29 | — | — | EP | disclosed |
| EP-2552458-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | Wayne State University (US) | 2013-02-06 | — | — | EP | disclosed |
| EP-0440647-A1 | LABELED NUCLEIC ACID PROBE | BIOGEN, INC. (US) | 1991-08-14 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| WO-1989012110-A1 | LABELED NUCLEIC ACID PROBE | BIOGEN, INC. (US) | 1989-12-14 | — | — | WO | disclosed |
| US-4876190-A | MEDICAL DIAGNOSIS, IMMUNOASSAY | BECTON DICKINSON & COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0314406-A1 | Peridinin-chlorophyll complex as fluorescent label | Becton, Dickinson and Company (US) | 1989-05-03 | — | — | EP | disclosed |
| US-4565696-A | ADMINISTERING TO PRODUCE ANTIBODIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-01-21 | — | — | US | disclosed |
| US-4542104-A | Phycobiliprotein fluorescent conjugates | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIV. (US) | 1985-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170028075-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | PAM, UACA, FLT1 | ALDH1A1 1885/4885KMT2A 2126/4885MAPT 2282/4885 |
| US-20130136697-A1 | INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES | UACA, PAM, JAK3 | ALDH1A1 1369/4885KMT2A 2985/4885MAPT 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.