SCHEMBL4958063

SCHEMBL4958063

N=C(N)c1ccc(NC(=O)NCC(=O)NCc2ccccn2)s1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.47
ALOX15 P16050 2/20 0.47
POLB P06746 1/20 0.46
KMT2A Q03164 4/20 0.46
HPGD P15428 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.45
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4960599 0.82 F7 (0.45)
SCHEMBL4960568 0.79 HPGD (0.54) RAB9ANPC1SMN1; SMN2POLBKMT2A
SCHEMBL5154948 0.77 ST14 (0.44) RAB9ANPC1SMN1; SMN2POLBHPGD
SCHEMBL4961414 0.76 F7 (0.67) NPC1POLB
SCHEMBL4958068 0.76 F7 (0.48)
SCHEMBL4959678 0.75 ALDH1A1 (0.43) SMN1; SMN2POLBKMT2AHPGDMEN1
SCHEMBL4959775 0.73 F7 (0.66)
SCHEMBL14590051 0.70 SMN1; SMN2 (0.65) RAB9ANPC1SMN1; SMN2ALOX15POLB
SCHEMBL1303744 0.69 SMN1; SMN2 (0.69) RAB9ANPC1SMN1; SMN2ALOX15POLB
SCHEMBL358181 0.69 SMN1; SMN2 (0.62) RAB9ANPC1SMN1; SMN2ALOX15POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312161-A1 Compounds For Stabilizing Factor VII Polypeptide Formulations NOVO NORDISK HEALTH CARE AG (CH) 2008-12-18 US disclosed
US-20080312161-A1 Compounds For Stabilizing Factor VII Polypeptide Formulations NOVO NORDISK HEALTH CARE AG (CH) 2008-12-18 US disclosed
US-20080312161-A1 Compounds For Stabilizing Factor VII Polypeptide Formulations NOVO NORDISK HEALTH CARE AG (CH) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312161-A1 Compounds For Stabilizing Factor VII Polypeptide Formulations F7, F5, F13B RAB9A 1217/4885NPC1 1908/4885SMN1; SMN2 817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.