SCHEMBL495814

SCHEMBL495814

CCOC(=O)c1ccccc1C(=O)OC

nearest known ligand 0.84

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.84
ALDH1A1 P00352 6/20 0.65
HSD17B10 Q99714 4/20 0.65
KDM4E B2RXH2 5/20 0.59
CDC25B P30305 3/20 0.58
LMNA P02545 2/20 0.57
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CFTR P13569 1/20 0.55
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
CDC25A P30304 1/20 0.54
CDC25C P30307 1/20 0.54
KMT2A Q03164 1/20 0.54
HPGD P15428 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
POLB P06746 1/20 0.53
ATM Q13315 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Phthalate SCHEMBL2173730 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL22296 0.92 TSHR (1.00) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL29404255 0.92 TSHR (1.00) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL5306972 0.92 TSHR (1.00) TSHRALDH1A1HSD17B10KDM4ECDC25B
SCHEMBL9877390 0.91 ALDH1A1 (0.77) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL21811188 0.91 TSHR (0.75) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL7520316 0.90 TSHR (0.95) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL30925693 0.90 TSHR (0.95) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL8577506 0.90 TSHR (0.95) TSHRALDH1A1HSD17B10KDM4ECDC25B
Diethyl Phthalate SCHEMBL19252611 0.90 TSHR (0.95) TSHRALDH1A1HSD17B10KDM4ECDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116769089-A Preparation process and device of polybutene-1 resin 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-116769088-A Preparation method of high isotactic polybutene-1 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-116769090-A Preparation method of butene-1 polymer 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-116769091-A Preparation method of polybutene-1 resin 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-116769083-A Preparation method and device of 1-butene polymer 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-116769095-A 1-butene solution polymerization method and device 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-116769096-A Preparation method of high isotactic polybutene-1 中国石油化工股份有限公司 2023-09-19 CN claimed
CN-115813863-A Microsphere capable of spontaneously agglomerating and preparation method thereof 广州因明生物医药科技股份有限公司 2023-03-21 CN claimed
CN-115340821-A Metal-based high-strength room-temperature-curing phenylamide ester silicon resin protective coating and preparation method and application thereof 国科广化精细化工孵化器(南雄)有限公司 2022-11-15 CN claimed
CN-108341899-A A kind of catalytic component, preparation method and applications being used for vinyl polymerization or combined polymerization based on alkoxyl magnesium carrier 任丘市利和科技发展有限公司 2018-07-31 CN claimed
EP-3172267-A1 RECYCLING PROCESS Worn Again Footwear And Accessories Limited (GB) 2017-05-31 EP claimed
CN-103962179-B Catalyst for acetylene method vinyl acetate synthesis 中国石油化工股份有限公司 2016-08-03 CN claimed
CN-103934024-B The synthetic method of vinyl acetate catalyst and vinyl acetate SINOPEC CORP. (CN) 2016-05-18 CN claimed
CN-103934033-B For the Catalysts and its preparation method of ethylene process synthesizing vinyl acetate SINOPEC CORP. (CN) 2016-05-18 CN claimed
WO-2016012755-A1 RECYCLING PROCESS WORN AGAIN FOOTWEAR AND ACCESSORIES LIMITED (GB) 2016-01-28 WO claimed
CN-103962179-A Catalyst used for acetylene method vinyl acetate synthesis CHINA PETROLEUM & CHEMICAL 2014-08-06 CN claimed
CN-103934024-A Catalyst for synthesis of vinyl acetate and synthetic method of vinyl acetate CHINA PETROLEUM & CHEMICAL 2014-07-23 CN claimed
CN-103934033-A Catalyst for synthesis of vinyl acetate by ethylene method and its preparation method CHINA PETROLEUM & CHEMICAL 2014-07-23 CN claimed
US-4640906-A ORGANOALUMINUM COMPOUND, PIPERIDINE DERIVATIVE AND SOLID FROM DIALKOXYMAGNESIUM COMPOUND, AROMATIC DIESTER AND HALOGENATED HYDROCARBON TOHO TITANIUM CO., LTD. (JP) 1987-02-03 US claimed
US-4102983-A ABSORPTION LIQUID CONTAINING MINERAL OIL SHOWA OIL CO., LTD. (JP) 1978-07-25 US claimed