Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179041 | 0.86 | POLB (0.65) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5888424 | 0.85 | POLB (0.56) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL774588 | 0.85 | POLB (0.56) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1647181 | 0.84 | GAA (0.53) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16841342 | 0.84 | POLB (0.50) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9313018 | 0.84 | POLB (0.50) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13947181 | 0.84 | POLB (0.63) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14354630 | 0.83 | ESR1 (0.49) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10306224 | 0.82 | ALDH1A1 (0.54) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29819513 | 0.81 | ALDH1A1 (0.58) | POLBNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293782-A1 | 1,1,3-Trioxo-1,2,5-Thiadiazolidines and Their Use as Ptp-Ases Inhibitors | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
| US-20070298348-A1 | Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method | FUJIFILM CORPORATION (JP) | 2007-12-27 | — | — | US | disclosed |
| US-7189501-B2 | Silver halide color photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293782-A1 | 1,1,3-Trioxo-1,2,5-Thiadiazolidines and Their Use as Ptp-Ases Inhibitors | PTPRS, IRS1, PTPMT1 | POLB 3613/4885NPC1 3787/4885RAB9A 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.