SCHEMBL4958843

SCHEMBL4958843

NCCCCC(N)C(=O)NCC(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCCCN)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC15A2 Q16348 1/20 0.50
TERT O14746 1/20 0.42
CD40 P25942 3/20 0.40
MMP2 P08253 1/20 0.39
C5AR1 P21730 2/20 0.38
ERAP2 Q6P179 3/20 0.36
LNPEP Q9UIQ6 3/20 0.36
OPRD1 P41143 1/20 0.36
ERAP1 Q9NZ08 1/20 0.36
NOD1 Q9Y239 1/20 0.36
PRMT5 O14744 1/20 0.35
CARM1 Q86X55 1/20 0.35
PRMT1 Q99873 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
PRMT7 Q9NVM4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4958851 1.00 SLC15A2 (0.50) SLC15A2TERTCD40MMP2C5AR1
SCHEMBL31453807 0.96 SLC15A2 (0.50) SLC15A2TERTCD40C5AR1ERAP2
SCHEMBL31514351 0.94 SLC15A2 (0.48) SLC15A2TERTCD40C5AR1ERAP2
SCHEMBL8832514 0.94 TERT (0.44) SLC15A2TERTCD40MMP2ERAP2
SCHEMBL2823387 0.94 TERT (0.44) SLC15A2TERTCD40MMP2ERAP2
SCHEMBL30670352 0.94 SLC15A2 (0.48) SLC15A2TERTCD40C5AR1ERAP2
SCHEMBL8832652 0.93 TERT (0.44) SLC15A2TERTCD40MMP2ERAP2
SCHEMBL31282809 0.93 TERT (0.42) SLC15A2TERTCD40MMP2
SCHEMBL9748489 0.92 SLC15A2 (0.46) SLC15A2TERTCD40MMP2ERAP2
SCHEMBL8427583 0.92 SLC15A2 (0.46) SLC15A2TERTCD40MMP2ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445431-B2 Peptides having separate domains; AIDS, cardiovascular disease, hepatitis. diabetes, cancer; side effect reduction THE OHIO STATE UNIVERSITY (US) 2013-05-21 US disclosed
US-20080188422-A1 Ligands Having Metal Binding Ability and Targeting Properties THE OHIO STATE UNIVERSITY RESEARCH OFFICE OF TECHNOLOGY LICENSING & COMMERCIALIZATION (US) 2008-08-07 US disclosed
WO-2005117997-A1 LIGANDS HAVING METAL BINDING ABILITY AND TARGETING PROPERTIES THE OHIO STATE UNIVERSITY (US) 2005-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188422-A1 Ligands Having Metal Binding Ability and Targeting Properties CNBP, GAA, SPR SLC15A2 1649/4885TERT 4068/4885CD40 1590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.