SCHEMBL4959241

SCHEMBL4959241

O=C(O)C(O)(CO)C(=O)CO

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701559 0.82 ALDH1A1 (0.39) ALDH1A1TSHROR51E2
SCHEMBL28576099 0.79 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL28599214 0.72
SCHEMBL626978 0.71 FAAH (0.50) ALDH1A1TSHROR51E2
SCHEMBL28206822 0.67 ALDH1A1 (0.30) ALDH1A1
SCHEMBL721800 0.65 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL722075 0.65 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL722035 0.65 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL11800153 0.65 TSHR (0.37) TSHR
SCHEMBL5572486 0.63 OR51E2 (0.30) OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018138195-A1 CELL-FREE PROTEIN SYNTHESIS SYSTEM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-08-02 WO claimed
EP-3354737-A1 CELL-FREE PROTEIN SYNTHESIS SYSTEM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-08-01 EP claimed
US-7314755-B2 Preservation of eukaryotic cells using reversible pore formation BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2008-01-01 US claimed
US-20050084481-A1 Preservation of eukaryotic cells BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2005-04-21 US claimed
CN-110199027-B Cell-free protein synthesis system 弗劳恩霍夫应用研究促进协会 2022-11-18 CN disclosed
US-11317623-B2 Cell-free protein synthesis system FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2022-05-03 US disclosed
EP-3574100-B1 CELL-FREE PROTEIN SYNTHESIS SYSTEM FRAUNHOFER GES FORSCHUNG (DE) 2021-12-22 EP disclosed
EP-3354737-B1 CELL-FREE PROTEIN SYNTHESIS SYSTEM FRAUNHOFER GES FORSCHUNG (DE) 2020-08-19 EP disclosed
WO-2018138195-A1 CELL-FREE PROTEIN SYNTHESIS SYSTEM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-08-02 WO disclosed
EP-3354737-A1 CELL-FREE PROTEIN SYNTHESIS SYSTEM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-08-01 EP disclosed
US-7314755-B2 Preservation of eukaryotic cells using reversible pore formation BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2008-01-01 US disclosed
US-20050084481-A1 Preservation of eukaryotic cells BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2005-04-21 US disclosed