Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 10/20 | 0.70 |
| ▸ | CA12 | O43570 | 8/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | GLA | P06280 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | CASP1 | P29466 | 3/20 | 0.70 |
| ▸ | CASP7 | P55210 | 3/20 | 0.70 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | ACHE | P22303 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | BCHE | P06276 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710930 | 0.98 | CA9 (0.72) | CA9CA12MCL1AKR1B1KDM4E | |
| SCHEMBL1535327 | 0.98 | CA9 (0.72) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL24641 | 0.83 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL29569228 | 0.83 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL6867015 | 0.83 | CA9 (1.00) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL8708221 | 0.81 | CA9 (0.96) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL30120615 | 0.81 | CA9 (0.96) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL1736697 | 0.81 | CA9 (0.96) | CA9CA12MCL1AKR1B1KDM4E | |
| Esculetin SCHEMBL29163498 | 0.81 | CA9 (0.96) | CA9CA12MCL1AKR1B1KDM4E | |
| SCHEMBL28917081 | 0.78 | CA9 (0.58) | CA9CA12MCL1AKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629197-B2 | Chemically patterned hydrogels, manufacture and use thereof | SHOICHET MOLLY (CA) | 2014-01-14 | — | — | US | disclosed |
| US-20080286360-A1 | Chemically patterned hydrogels, manufacture and use thereof | SHOICHET MOLLY | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286360-A1 | Chemically patterned hydrogels, manufacture and use thereof | CD44, CRYAA, VCL | CA9 1306/4885CA12 1347/4885MCL1 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.