Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27504982 | 0.83 | POLB (0.58) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL14719879 | 0.81 | MEN1 (0.77) | MEN1KMT2AALDH1A1LMNATAAR1 | |
| SCHEMBL7117183 | 0.79 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL9270176 | 0.76 | SIGMAR1 (0.50) | MEN1KMT2ATAAR1POLBIDO1 | |
| SCHEMBL10395199 | 0.75 | SMN1; SMN2 (0.64) | ALDH1A1LMNACYP3A4KDM4EGAA | |
| SCHEMBL11703182 | 0.75 | CA1 (0.59) | MEN1KMT2AALDH1A1KDM4ECA2 | |
| SCHEMBL28028806 | 0.74 | MEN1 (0.90) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL9320464 | 0.74 | ATM (0.58) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL22472095 | 0.74 | ATM (0.58) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL27739790 | 0.73 | HPGD (0.56) | MEN1KMT2AALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984370-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Crystalgenomics, Inc. (KR) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007083978-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-07-26 | — | — | WO | disclosed |