Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294672 | 0.87 | LMNA (0.51) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL3681492 | 0.86 | LMNA (0.51) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL3681491 | 0.86 | LMNA (0.51) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL1150088 | 0.83 | LMNA (0.46) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL1150086 | 0.83 | LMNA (0.46) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL1150084 | 0.83 | LMNA (0.46) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL295824 | 0.83 | LMNA (0.58) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL295825 | 0.83 | LMNA (0.58) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL3684631 | 0.82 | LMNA (0.45) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL3684630 | 0.82 | LMNA (0.45) | LMNATSHRCYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463706-B1 | PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES | SUMITOMO CHEMICAL CO (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-7262320-B2 | Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20050090685-A1 | Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1463706-A1 | PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES | Sumitomo Chemical Company, Limited (JP) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059861-A1 | PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-24 | — | — | WO | disclosed |
| US-6011169-A | Process for producing optically active cyclopropanecaboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0891965-A1 | Process for producing optically active cyclopropanecarboxylic acid esters | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090685-A1 | Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives | ADSL, CMPK1, MRPL21 | LMNA 4209/4885TSHR 3876/4885CYP1A2 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.