1,3-Propanediol

1,3-Propanediol

SCHEMBL4960366

C=C.CC(C)O.OCCCO.OCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
LMNA P02545 3/20 0.40
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 6/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3-Propanediol SCHEMBL4960368 0.93 ALDH1A1 (0.46) ALDH1A1LMNATDP1SMN1; SMN2TSHR
1,3-Propanediol SCHEMBL8809902 0.89
Isopropyl Alcohol SCHEMBL564846 0.89 ALDH1A1 (0.50) ALDH1A1LMNATDP1TSHR
1,3-Propanediol SCHEMBL28201030 0.83 TDP1 (0.41) ALDH1A1LMNATDP1SMN1; SMN2TSHR
1,3-Propanediol SCHEMBL10780274 0.82
1,4-Butanediol SCHEMBL2293967 0.82 ALDH1A1 (0.50) ALDH1A1LMNATDP1SMN1; SMN2TSHR
Isopropyl Alcohol SCHEMBL564847 0.82
Isopropyl Alcohol SCHEMBL8328017 0.82 ALDH1A1 (0.60) ALDH1A1LMNATDP1TSHR
Isopropyl Alcohol SCHEMBL28189096 0.82 ALDH1A1 (0.60) ALDH1A1LMNATDP1TSHR
1,3-Propanediol SCHEMBL3683037 0.82 TSHR (0.50) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2007210-A2 COMPOSITIONS COMPRISING MONO AND DI ESTERS OF BIOLOGICALLY-BASED 1.3-PROPANEDIOL DuPont Tate & Lyle Bio Products Company, LLC (US) 2008-12-31 EP disclosed
WO-2008123845-A2 COMPOSITIONS COMPRISING MONO AND DI ESTERS OF BIOLOGICALLY-BASED 1.3-PROPANEDIOL DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) 2008-10-16 WO disclosed