Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029746 | 0.81 | TGFBR1 (0.38) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL15223622 | 0.81 | CA1 (0.39) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9401922 | 0.79 | MAPT (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL10445512 | 0.79 | MAPT (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL10445510 | 0.79 | MAPT (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9401736 | 0.79 | MAPT (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9401725 | 0.79 | MAPT (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9401932 | 0.79 | MAPT (0.37) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL15222251 | 0.79 | TDP1 (0.40) | MAPTALDH1A1NPSR1RECQLCA12 | |
| SCHEMBL23607312 | 0.79 | CA1 (0.52) | MAPTNPSR1KMT2ACA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470815-B1 | Selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2008-12-30 | — | — | US | disclosed |