Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445510 | 1.00 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10445512 | 1.00 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9401922 | 1.00 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9401725 | 1.00 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9401736 | 1.00 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7376788 | 0.84 | CTSK (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7376786 | 0.84 | CTSK (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7377350 | 0.84 | CTSK (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL4960459 | 0.79 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL23849248 | 0.75 | CA1 (0.52) | MAPTKMT2ANPSR1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |