Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610978 | 1.00 | KMT2A (0.59) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL610977 | 1.00 | KMT2A (0.59) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL610922 | 0.92 | KMT2A (0.69) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL613077 | 0.91 | KMT2A (0.68) | KMT2AHSD11B1LMNAMEN1TSHR | |
| SCHEMBL610255 | 0.88 | EPHX2 (0.66) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL610256 | 0.88 | EPHX2 (0.66) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL4963791 | 0.88 | EPHX2 (0.66) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL612938 | 0.88 | HSD11B1 (0.62) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL4963969 | 0.88 | HSD11B1 (0.62) | KMT2ATDP1HSD11B1LMNAMEN1 | |
| SCHEMBL612937 | 0.88 | HSD11B1 (0.62) | KMT2ATDP1HSD11B1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |