Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 6/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4139204 | 0.86 | RXRA (0.38) | FFAR4HRH4RXRALTC4SCNR2 | |
| SCHEMBL4139481 | 0.84 | RXRA (0.41) | FFAR4HRH4RXRALTC4SPDE4B | |
| SCHEMBL4139206 | 0.83 | FFAR4 (0.34) | FFAR4HRH4RXRALTC4SPTK2 | |
| SCHEMBL16160338 | 0.77 | LTC4S (0.36) | FFAR4HRH4LTC4SCNR2PDE4B | |
| SCHEMBL4139575 | 0.76 | PDE4B (0.40) | RXRAPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3215050 | 0.73 | RXRA (0.47) | RXRALTC4SPDE4BPDE4APDE4C | |
| SCHEMBL4140868 | 0.73 | HRH4 (0.41) | HRH4RXRA | |
| Hydrochloric Acid SCHEMBL4141190 | 0.72 | HRH4 (0.40) | HRH4RXRA | |
| SCHEMBL3207140 | 0.71 | RXRA (0.43) | RXRALTC4SPDE4BPDE4APDE4C | |
| SCHEMBL3218504 | 0.71 | LTC4S (0.46) | RXRALTC4SPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888528-A2 | PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceuticals Corporation (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135828-A2 | TRISUBSTITUTED AMINES AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-12-21 | — | — | WO | disclosed |