Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959698 | 0.83 | RXRA (0.55) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL6675620 | 0.72 | RXRA (0.65) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4959128 | 0.72 | RXRA (0.67) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL6673775 | 0.70 | RXRA (0.57) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL6676520 | 0.70 | RXRA (0.56) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4960616 | 0.69 | MAPT (0.35) | RXRAMAPTHCAR3PPARGNR1H3 | |
| SCHEMBL4960622 | 0.68 | MAPT (0.35) | RXRAMAPTHCAR3PPARGNR1H3 | |
| SCHEMBL4956986 | 0.67 | RXRA (0.49) | RXRAMAPTPPARGNR1H3HNF4A | |
| SCHEMBL4960820 | 0.66 | RXRA (0.52) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4960828 | 0.66 | RXRA (0.52) | RXRAPPARGNR1H3HNF4ARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351685-B1 | STABILIZED FORMULATION OF SELECTIVE LIGANDS OF RETINOIC ACID GAMMA-RECEPTORS | JOHNSON & JOHNSON CONSUMER (US) | 2008-02-27 | — | — | EP | disclosed |