Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960692 | 1.00 | P2RX1 (0.59) | P2RX1MEN1KMT2ARAB9AKCNMA1 | |
| SCHEMBL4960624 | 0.95 | P2RX1 (0.62) | P2RX1MEN1KMT2ARAB9AKCNMA1 | |
| SCHEMBL4960611 | 0.95 | P2RX1 (0.62) | P2RX1MEN1KMT2ARAB9AKCNMA1 | |
| SCHEMBL5668775 | 0.85 | KCNMA1 (0.61) | P2RX1MEN1KMT2AKCNMA1HTT | |
| SCHEMBL5666838 | 0.84 | P2RX1 (0.69) | P2RX1MEN1KMT2ARAB9AHTT | |
| SCHEMBL5900771 | 0.84 | MEN1 (0.65) | P2RX1MEN1KMT2ARAB9AHTT | |
| SCHEMBL5666677 | 0.84 | KDM4E (0.70) | P2RX1MEN1KMT2ARAB9AKCNMA1 | |
| SCHEMBL1964469 | 0.83 | RORC (0.62) | P2RX1MEN1KMT2AKCNMA1HTT | |
| SCHEMBL5668773 | 0.82 | P2RX1 (0.66) | P2RX1MEN1KMT2ARAB9AHTT | |
| SCHEMBL31583073 | 0.82 | P2RX1 (0.66) | P2RX1MEN1KMT2ARAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094909-A2 | QUINAZOLINONE AND FUSED PYRIMIDINONE COMPOUNDS AND THEIR USE IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-08-07 | — | — | WO | disclosed |