Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611004 | 1.00 | LTA4H (0.38) | LTA4HLMNADNM1TDP1CYP1A2 | |
| SCHEMBL7382992 | 0.94 | LTA4H (0.39) | LTA4HLMNADNM1TDP1CYP3A4 | |
| SCHEMBL1610492 | 0.94 | LTA4H (0.39) | LTA4HLMNADNM1TDP1CYP3A4 | |
| SCHEMBL17558059 | 0.92 | DNM1 (0.41) | LTA4HLMNADNM1TDP1TSHR | |
| SCHEMBL1610523 | 0.92 | DNM1 (0.41) | LTA4HLMNADNM1TDP1TSHR | |
| SCHEMBL3939370 | 0.92 | DNM1 (0.41) | LTA4HLMNADNM1TDP1TSHR | |
| SCHEMBL26092597 | 0.92 | DNM1 (0.41) | LTA4HLMNADNM1TDP1TSHR | |
| SCHEMBL8735182 | 0.92 | DNM1 (0.41) | LTA4HLMNADNM1TDP1TSHR | |
| SCHEMBL1610832 | 0.87 | APP (0.36) | LTA4HLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6158433 | 0.87 | APP (0.36) | LTA4HLMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177169-A | Process for preparing monovinyl-functionalized dialkylphosphinic acids, salts and esters thereof and use thereof | CLARIANT FINANCE BVI LTD | 2011-09-07 | — | — | CN | disclosed |
| EP-1880987-A1 | PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE | Sankyo Agro Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| CN-1039321-C | New beta-amino-alpha-hydroxycarboxylic acids and their use | SANKYO CO (JP) | 1998-07-29 | — | — | CN | disclosed |
| CN-1064683-A | New beta-amino-alpha-hydroxycarboxylic acids and uses thereof | SANKYO CO (JP) | 1992-09-23 | — | — | CN | disclosed |
| EP-0498680-A1 | New beta-amino-alpha-hydroxycarboxylic acids and their use | Sankyo Company Limited (JP) | 1992-08-12 | — | — | EP | disclosed |