Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brodimoprim SCHEMBL30659008 | 1.00 | DHFR (0.77) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| Brodimoprim SCHEMBL11593445 | 0.99 | DHFR (0.75) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| Brodimoprim SCHEMBL18694733 | 0.90 | DHFR (0.64) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| Aditeren SCHEMBL1230789 | 0.88 | DHFR (0.81) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| SCHEMBL11946659 | 0.88 | DHFR (0.64) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| SCHEMBL6557137 | 0.87 | DHFR (0.70) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| Trimethoprim SCHEMBL24506 | 0.87 | DHFR (1.00) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| SCHEMBL9284945 | 0.87 | DHFR (0.79) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| Trimethoprim SCHEMBL2637561 | 0.87 | DHFR (1.00) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 | |
| Trimethoprim SCHEMBL29462189 | 0.87 | DHFR (1.00) | DHFRMEN1SLC22A1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2905 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026086804-A1 | MULTILAYER-REGULATED GENE EDITING SYSTEM AND USE THEREOF | 自如基因科技（深圳）有限公司 | 2026-04-30 | — | — | WO | claimed |
| EP-4536217-A1 | CO-AGENTS AS THERAPY AGAINST ANAEROBIC PATHOGENS | Fleurir Abx LLC (US) | 2025-04-16 | — | — | EP | claimed |
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| US-20240293434-A1 | COMBINATION THERAPY EFFECTIVE AGAINST MICROORGANISMS, INCLUDING DRUG RESISTANT MICROORGANISMS | FLEURIR ABX LLC (US) | 2024-09-05 | — | — | US | claimed |
| US-20240173512-A1 | METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS | STREETERVILLE CAPITAL, LLC | 2024-05-30 | — | — | US | claimed |
| US-11890421-B2 | Methods for potentiating antimicrobial agents | BEYOND AIR LTD (IL) | 2024-02-06 | — | — | US | claimed |
| WO-2023239822-A1 | CO-AGENTS AS THERAPY AGAINST ANAEROBIC PATHOGENS | FLEURIR ABX LLC (US) | 2023-12-14 | — | — | WO | claimed |
| US-20230398101-A1 | Co-agents as Therapy Against Anaerobic Pathogens | FLEURIR ABX LLC (US) | 2023-12-14 | — | — | US | claimed |
| EP-4273248-A2 | DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN | Braingene AB (SE) | 2023-11-08 | — | — | EP | claimed |
| EP-3458579-B1 | DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN | BRAINGENE AB (SE) | 2023-07-05 | — | — | EP | claimed |
| US-5543417-A | 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent | MERCK & CO., INC. (US) | 1996-08-06 | — | — | US | claimed |
| WO-1996012817-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| EP-0313630-B1 | SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME | DEUTSCHES AUSSÄTZIGEN HILFSWERK E.V. (DE) | 1992-09-16 | — | — | EP | claimed |
| EP-0313630-A1 | SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME. | DEUTSCHES AUSSATZIGEN HILFSWER (DE) | 1989-05-03 | — | — | EP | claimed |
| WO-1988008842-A2 | SUBSTITUTED 2-ACYLPYRIDIN-alpha-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME | DEUTSCHES AUSSÄTZIGEN HILFSWERK E.V. (DE) | 1988-11-17 | — | — | WO | claimed |
| US-4599416-A | Process for the preparation of aqueous solutions of potentiated sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1986-07-08 | — | — | US | claimed |
| EP-0043055-A1 | Combinations of therapeutically active substances, process for their manufacture and their use and means containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-01-06 | — | — | EP | claimed |
| US-4076810-A | Benzylpyrimidine antibacterial composition | HOFFMANN-LA ROCHE INC. (US) | 1978-02-28 | — | — | US | claimed |
| US-4024145-A | Benzylpyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1977-05-17 | — | — | US | claimed |