Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535212 | 1.00 | CYP3A4 (0.52) | CYP3A4TDP1ACHETSHRESR1 | |
| SCHEMBL16424436 | 0.98 | CYP3A4 (0.50) | CYP3A4TDP1ACHETSHRESR1 | |
| Hydrochloric Acid SCHEMBL10793333 | 0.95 | CYP3A4 (0.48) | CYP3A4TDP1ACHETSHRESR1 | |
| SCHEMBL49858 | 0.95 | CYP3A4 (0.52) | CYP3A4TDP1ACHETSHRESR1 | |
| SCHEMBL31532278 | 0.93 | CYP3A4 (0.50) | CYP3A4TDP1ACHETSHRESR1 | |
| Iodide SCHEMBL30903480 | 0.93 | CYP3A4 (0.50) | CYP3A4TDP1ACHETSHRESR1 | |
| SCHEMBL31531976 | 0.93 | CYP3A4 (0.50) | CYP3A4TDP1ACHETSHRESR1 | |
| SCHEMBL3717033 | 0.93 | CYP3A4 (0.57) | CYP3A4TDP1ACHETSHRESR1 | |
| Hydrochloric Acid SCHEMBL11571801 | 0.93 | CYP3A4 (0.50) | CYP3A4TDP1ACHETSHRESR1 | |
| Hydrochloric Acid SCHEMBL31198728 | 0.93 | CYP3A4 (0.50) | CYP3A4TDP1ACHETSHRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507263-B1 | EFFICIENT CATALYST FOR THE FORMATION OF POLYARYL HYDROCARBONS SUITABLE AS PRECURSORS FOR POLYDENTATE ORGANOPHOSPHORUS CATALYST LIGANDS | EASTMAN CHEM CO (US) | 2024-06-19 | — | — | EP | claimed |
| CN-108003092-B | Synthetic method of 2, 3-dichloropyridine | 重庆中邦科技有限公司 | 2021-04-02 | — | — | CN | claimed |
| US-9975833-B2 | Efficient catalyst for the formation of polyaryl hydrocarbons suitable as precursors for polydentate organophosphorus catalyst ligands | EASTMAN CHEMICAL COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-20180057435-A1 | EFFICIENT CATALYST FOR THE FORMATION OF POLYARYL HYDROCARBONS SUITABLE AS PRECURSORS FOR POLYDENTATE ORGANOPHOSPHORUS CATALYST LIGANDS | EASTMAN CHEMICAL COMPANY (US) | 2018-03-01 | — | — | US | claimed |
| EP-2980092-B1 | BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME | KURARAY CO (JP) | 2017-10-04 | — | — | EP | claimed |
| US-20160052947-A1 | BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME | KURARAY CO., LTD. (JP) | 2016-02-25 | — | — | US | claimed |
| EP-2980092-A1 | BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME | Kuraray Co., Ltd. (JP) | 2016-02-03 | — | — | EP | claimed |
| US-5365007-A | Nickel compound with phosphine and phosphated alumina | PHILLIPS PETROLEUM COMPANY (US) | 1994-11-15 | — | — | US | claimed |
| US-5286696-A | Using an nickel, phosphine complex | PHILLIPS PETROLEUM COMPANY (US) | 1994-02-15 | — | — | US | claimed |
| US-5260499-A | Nickel compound, phosphine compound, organoaluminum compound, perfluorosulfonate polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-11-09 | — | — | US | claimed |
| US-4482640-A | NICKEL COMPOUND, PHOSPHINE, CARBOXYLIC ACID AS CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1984-11-13 | — | — | US | claimed |
| EP-0043382-B1 | PREPARATION OF ISOBUTYRIC ACID AND ESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-16 | — | — | EP | claimed |
| EP-0020473-B1 | PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM | NAPP SYSTEMS (USA) INC. (US) | 1983-06-22 | — | — | EP | claimed |
| EP-0043382-A1 | Preparation of isobutyric acid and esters | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-13 | — | — | EP | claimed |
| US-4292437-A | USING A PALLADIUM-ORTHO-SUBSTITUTED TRIARYL PHOSPHINE COMPLEX AS CATALYST FOR THE CARBONYLATION OF PROPYLENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-29 | — | — | US | claimed |
| US-4283481-A | COMPRISING AN UNSATURATED MONOMER, POLYMER, INITIATOR AND ACTIVATOR | NAPP SYSTEMS (USA) INC. (US) | 1981-08-11 | — | — | US | claimed |
| EP-0020473-A1 | PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM. | NAPP SYSTEMS INC (US) | 1981-01-07 | — | — | EP | claimed |
| US-4233391-A | PRINTING PLATES | NAPP SYSTEMS (USA) INC. (US) | 1980-11-11 | — | — | US | claimed |
| EP-0020473-A4 | PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM. | NAPP SYSTEMS INC (US) | 1980-10-16 | — | — | EP | claimed |
| WO-1980000623-A1 | PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM | NAPP SYSTEMS INC (US) | 1980-04-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057435-A1 | EFFICIENT CATALYST FOR THE FORMATION OF POLYARYL HYDROCARBONS SUITABLE AS PRECURSORS FOR POLYDENTATE ORGANOPHOSPHORUS CATALYST LIGANDS | DDT, HDHD5, HPD | CYP3A4 90/4885TDP1 344/4885ACHE 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.