Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 14/20 | 0.46 |
| ▸ | TACR2 | P21452 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963091 | 0.89 | LMNA (0.60) | LMNAL3MBTL1TACR3TACR2TP53 | |
| SCHEMBL4963768 | 0.86 | LMNA (0.52) | LMNAL3MBTL1TACR3TACR2TP53 | |
| SCHEMBL4963863 | 0.85 | LMNA (0.54) | LMNAL3MBTL1TACR3TACR2TP53 | |
| SCHEMBL4961927 | 0.83 | LMNA (0.52) | LMNAL3MBTL1TACR3TACR2TP53 | |
| SCHEMBL4961957 | 0.81 | TACR3 (0.51) | LMNAL3MBTL1TACR3TACR2 | |
| SCHEMBL4964876 | 0.81 | TACR3 (0.51) | LMNAL3MBTL1TACR3 | |
| SCHEMBL5047970 | 0.81 | LMNA (0.67) | LMNAL3MBTL1TACR3TACR2TP53 | |
| SCHEMBL16553849 | 0.79 | LMNA (0.67) | LMNAL3MBTL1TACR3TACR2TP53 | |
| SCHEMBL4962172 | 0.79 | TACR3 (0.50) | LMNAL3MBTL1TACR3 | |
| SCHEMBL5049830 | 0.79 | LMNA (0.67) | LMNAL3MBTL1TACR3TACR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896418-A1 | QUINOLINE 3 -SULFONATE ESTERS AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-03-12 | — | — | EP | claimed |
| WO-2006137789-A1 | Quinoline 3 -sulfonate esters as NK3 receptor modulators | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | WO | claimed |
| EP-1896418-A1 | QUINOLINE 3 -SULFONATE ESTERS AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006137789-A1 | Quinoline 3 -sulfonate esters as NK3 receptor modulators | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | WO | disclosed |