Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962848 | 0.89 | HTT (0.47) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL4966420 | 0.85 | HTT (0.42) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL4960099 | 0.85 | HTT (0.39) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL5242756 | 0.84 | HTT (0.49) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL4972279 | 0.82 | HTT (0.43) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5191003 | 0.82 | HTT (0.47) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL5194886 | 0.82 | HTT (0.45) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL4965536 | 0.81 | HTT (0.43) | HTTALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL3812486 | 0.81 | GABRA1 (0.53) | HTTGABRA1GABRB2KDM4E | |
| Formic Acid SCHEMBL5161456 | 0.79 | HTT (0.44) | HTTALDH1A1HPGDMDH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879904-A1 | 4\" AMINO LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2008-01-23 | — | — | EP | disclosed |
| EP-1756135-A1 | ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006120545-A1 | 4' AMINO LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2006-11-16 | — | — | WO | disclosed |
| WO-2005108412-A1 | ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) | 2005-11-17 | — | — | WO | disclosed |