Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304363 | 0.70 | TSHR (0.57) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL4595029 | 0.69 | TSHR (0.50) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL29029703 | 0.69 | ALDH1A1 (0.42) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL2098784 | 0.68 | GPR35 (0.57) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL3536339 | 0.68 | TSHR (0.45) | TSHRALDH1A1TDP1CYP3A4LMNA | |
| SCHEMBL11852169 | 0.68 | MAPK1 (0.50) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11852183 | 0.68 | MAPK1 (0.50) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11758012 | 0.68 | TDP1 (0.55) | GPR35TSHRTDP1CYP1A2LMNA | |
| SCHEMBL8658889 | 0.68 | CYP1A2 (0.55) | GPR35TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL10614473 | 0.67 | GPR35 (0.53) | GPR35TSHRALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |