Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960983 | 0.95 | SMPD1 (0.49) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7088529 | 0.93 | KDM4E (0.44) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4963469 | 0.87 | MRGPRX4 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL4962160 | 0.86 | MRGPRX4 (0.43) | SMN1; SMN2NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL5889681 | 0.82 | SMPD1 (0.47) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8253237 | 0.82 | NPC1 (0.55) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7088530 | 0.81 | KDM4E (0.45) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5781307 | 0.80 | MRGPRX4 (0.47) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4962864 | 0.78 | BCHE (0.53) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3950505 | 0.78 | PTGER4 (0.62) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7238830-B2 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2001-11-08 | — | — | US | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | DNPEP, ANPEP, ASNS | HPGD 3550/4885ALDH1A1 3319/4885SMN1; SMN2 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.