Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962160 | 0.91 | MRGPRX4 (0.43) | MRGPRX4FFAR4MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL7088529 | 0.90 | KDM4E (0.44) | MRGPRX4MAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL4963434 | 0.87 | HPGD (0.50) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL4960983 | 0.87 | SMPD1 (0.49) | SMN1; SMN2NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL5889950 | 0.87 | MRGPRX4 (0.50) | MRGPRX4FFAR4MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL5781307 | 0.82 | MRGPRX4 (0.47) | MRGPRX4FFAR4MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL12295554 | 0.81 | MRGPRX4 (0.68) | MRGPRX4FFAR4MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4962864 | 0.80 | BCHE (0.53) | MAPTL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4704085 | 0.79 | FFAR4 (0.63) | MRGPRX4FFAR4MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4963465 | 0.78 | MRGPRX4 (0.54) | MRGPRX4FFAR4MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7238830-B2 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-7115296-B2 | N-alkylaspartyl amide derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-6761922-B2 | MIXING AN ASPARTYL DIPEPTIDE ESTER COMPOUND OR SALT WITH A SOLID FILLER SELECTED FROM SUGAR, SUGAR ALCOHOL, OLIGOSACCHARIDE AND POLYSACCHARIDE | AJINOMOTO CO., INC. (JP) | 2004-07-13 | — | — | US | disclosed |
| US-20040105928-A1 | Sweetener compositions and uses thereof | AJINOMOTO CO. INC (JP) | 2004-06-03 | — | — | US | disclosed |
| US-20040071851-A1 | Novel N-alkylaspartyl amide derivative and sweetening agent | AJINOMOTO CO. INC (JP) | 2004-04-15 | — | — | US | disclosed |
| US-6689902-B2 | REDUCTIVE ALKYLATION | AJINOMOTO CO., INC. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-6652901-B2 | Sweetener compositions and uses thereof | AJINOMOTO CO., INC. (JP) | 2003-11-25 | — | — | US | disclosed |
| CN-1407991-A | Solid sweetener composition, liquid sweetener composition, and use thereof | AJINOMOTO KK (JP) | 2003-04-02 | — | — | CN | disclosed |
| US-20030059511-A1 | Sweetener compositions and uses thereof | AJINOMOTO CO., INC. (JP) | 2003-03-27 | — | — | US | disclosed |
| US-20030044502-A1 | Sweetener compositions containing aspartyl dipeptide ester compounds | AJINOMOTO CO. INC (JP) | 2003-03-06 | — | — | US | disclosed |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | AJINOMOTO CO., INC. (JP) | 2003-02-13 | — | — | US | disclosed |
| CN-1395551-A | Novel arylpropionaldehyde derivatives and production and use of the same | AJINOMOTO KK (JP) | 2003-02-05 | — | — | CN | disclosed |
| CN-1378557-A | Sweetener compositions with high degree of sweeteness having improved sweeteness, corrigents and utilization thereof | AJINOMOTO KK (JP) | 2002-11-06 | — | — | CN | disclosed |
| EP-1249442-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-16 | — | — | EP | disclosed |
| EP-1223175-A1 | SOLID SWEETENER COMPOSITIONS, LIQUID SWEETENER COMPOSITIONS AND UTILIZATION THEREOF | Ajinomoto Co., Inc. (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-1221448-A1 | SWEETENER COMPOSITIONS WITH HIGH DEGREE OF SWEETNESS HAVING IMPROVED SWEETNESS, CORRIGENTS AND UTILIZATION THEREOF | Ajinomoto Co., Inc. (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2001-11-08 | — | — | US | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | DNPEP, ANPEP, ASNS | MRGPRX4 1939/4885FFAR4 1237/4885MAPT 1623/4885 |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | ALDH7A1, ASPH, DDC | MRGPRX4 2055/4885FFAR4 386/4885MAPT 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.